Kneeling-induced calf ischemia: a pilot study in apparently healthy European young subjects

Ramondou, Pierre; Hersant, Jeanne; Bernardeau, Elise; Moumneh, Thomas; Feuilloy, Mathieu; Henni, Samir; Ábrahám, Pierre

doi:10.1007/s00421-021-04764-8

Cited by 2 publications

(1 citation statement)

References 42 publications

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“…These are all practices that laypersons can easily learn and perform. Additionally, some positions in which people may nod, such as kneeling or hyperflexion at the waist, may theoretically present a risk of distal tissue injury from arterial kinking [ 21 ] and acute compartment syndrome [ 22 ]. Moving people who have nodded in awkward positions onto their side should be encouraged.…”

Section: Harm Reduction Strategiesmentioning

confidence: 99%

Reducing the harms of xylazine: clinical approaches, research deficits, and public health context

Zagorski,

Hosey,

Moraff

et al. 2023

Harm Reduct J

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Objectives Xylazine has emerged as a consistent part of the unregulated drug supply in recent months. We discuss major domains of xylazine’s harm, current knowledge deficits, clinical and harm reduction strategies for minimizing harm, and xylazine’s public health and policy context. As an interdisciplinary team from across the USA, we have pooled our knowledge to provide an overview of xylazine’s current and emerging contexts. Methods To inform this essay, the pertinent literature was reviewed, clinical knowledge and protocols were shared by multiple clinicians with direct expertise, and policy and public health context were added by expert authors. Results We describe xylazine’s major harm domains—acute poisoning, extended sedation, and wounds, along with anemia and hyperglycemia, which have been reported anecdotally but lack as clear of a connection to xylazine. Current successful practices for xylazine wound care are detailed. Understanding xylazine’s epidemiology will also require greater investment in drug checking and surveillance. Finally, approaches to community-based wound care are discussed, along with an orientation to the larger policy and public health context. Conclusions Addressing the harms of xylazine requires interdisciplinary participation, investment in community-based harm reduction strategies, and improved drug supply surveillance. The relatively unique context of xylazine demands buy-in from public health professionals, harm reduction professionals, clinicians, basic science researchers, policymakers and more.

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Section: Harm Reduction Strategiesmentioning

confidence: 99%

Reducing the harms of xylazine: clinical approaches, research deficits, and public health context

Zagorski,

Hosey,

Moraff

et al. 2023

Harm Reduct J

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Acute arterial stiffness responses to on-ball balance exercises in young and middle-aged adults: Role of posture and cumulative effects

Chen

Miao²,

Zhou³

et al. 2023

Front. Physiol.

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Objective: To examine the acute arterial stiffness changes after maintaining one bout of balance on Swiss ball using different postures in young and middle-aged adults, and to evaluate the cumulative exposure effects on arterial stiffness after multiple exercise bouts in middle-aged adults.Methods: Using crossover design, we first enrolled 22 young adults (24.0 ± 1.1 years) and randomized them to non-exercise control (CON), on-ball balance exercise trial lasting 1 × 5 min in kneeling posture (K1) and sitting posture (S1). In a following crossover experiment, 19 middle-aged adults (53.0 ± 4.7 years) were randomized to non-exercise control (CON), on-ball balance exercise trial lasting 1 × 5 min in kneeling posture (K1) and in sitting posture (S1), and on-ball balance exercise trial lasting 2 × 5 min in kneeling posture (K2) and in sitting posture (S2). Cardio-ankle vascular index (CAVI), an indicator of systemic arterial stiffness, was measured at baseline (BL), immediately after (0 min), and every 10 min after exercise. CAVI changes from BL in the same trial (⊿CAVI) were used for analysis.Results: In K1 trial, ⊿CAVI decreased significantly at 0 min (p < 0.05) in both young and middle-aged adults; however in S1 trial, ⊿CAVI at 0 min increased significantly in young adults (p < 0.05), with ⊿CAVI tending to increase in middle-aged adults. Bonferroni post-test revealed that at 0 min, ⊿CAVI of K1 in both young and middle-aged adults, and ⊿CAVI of S1 in young adults differed significantly from that of CON (p < 0.05). In middle-aged adults, ⊿CAVI decreased significantly at 10 min compared to BL in K2 trial (p < 0.05), and increased at 0 min compared to BL in S2 trial (p < 0.05); however, difference compared to CON was not significant.Conclusion: Single on-ball balance bout in kneeling posture improved arterial stiffness transiently in both young and middle-aged adults; however, sitting posture elicited opposite changes, and this happened only in young adults. Multiple balance bouts resulted in no significant change in arterial stiffness in middle-aged adults.

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Kneeling-induced calf ischemia: a pilot study in apparently healthy European young subjects

Cited by 2 publications

References 42 publications

Reducing the harms of xylazine: clinical approaches, research deficits, and public health context

Reducing the harms of xylazine: clinical approaches, research deficits, and public health context

Acute arterial stiffness responses to on-ball balance exercises in young and middle-aged adults: Role of posture and cumulative effects

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