Described by Jefferson in 1968, Jael's syndrome is described as an intentional injury caused by a knife in the skull or face. The clinical and radiographic diagnosis is essential to know the risk of damage to the anatomical structures and the location of the foreign body, treatment includes removal, wound examination, suture, tetanus immunization and antibiotic prescription. This article describes the clinical case of a male patient with knife wound with a foreign blade in the buccal, masseter and mastoid region and its surgical treatment.