RESEARCHBackground. Although emergency contraception (EC) is widely available, its use is surrounded by many controversies. Overall, it seems to be underutilised worldwide. Objectives. To determine healthcare professionals᾽ knowledge, attitudes and perceptions regarding EC, and how frequently they encounter, educate and issue it to patients. Methods. A questionnaire-based survey of doctors and nurses (volunteers) working in obstetrics and gynaecology was conducted in 3 public hospitals and 17 clinics in Pietermaritzburg, KwaZulu-Natal Province, South Africa. Data were analysed using SPSS. Results. Sixty-seven (25%) doctors and 201 (75%) nurses participated in the survey. Awareness of the three ECs available in the public sector overall was 56.4%, and 62.7% of participants could prescribe one EC correctly. Only 39.6% knew that EC pills prevent ovulation. Seventy-six percent thought that the use of EC could lead to high-risk sexual behaviour, high risk of transmission of HIV and non-use of other forms of contraception. Only 7.8% saw patients seeking EC often, 5.6% issued it often and 23.5% educated patients about it often. Conclusion. Participants were familiar with EC, but lacked accurate and detailed knowledge about its mechanism of action and had misperceptions on its social impact. They seldom prescribed it. It is estimated that about 41.0% of the 208 million pregnancies that occurred worldwide in 2008 were unintended.[1] East and Central Africa have the highest rates of unintended pregnancies and about 14 million unintended pregnancies are estimated to occur in subSaharan Africa annually. [1,2] Unintended pregnancies are resolved differently by women. Globally, there were an estimated 42 million induced abortions in 2003, of which 48% were unsafe and 97% of the unsafe abortions were performed in developing countries.[3] The World Health Organization (WHO) estimated that 21.6 million unsafe abortions occurred worldwide in 2008, an increase from 19.7 million in 2003, [4] with Eastern and Central Africa having the highest rates.[5] Unsafe abortions have a negative impact on maternal morbidity and mortality. A reduction in unintended pregnancies may result in a reduction of unsafe abortions, hence lowering maternal mortality.In situations where there is unprotected sexual intercourse or contraceptive method failure, emergency contraception (EC) may be used to prevent unintended pregnancies. Although EC is widely available in many countries, its use has been marred with controversies and misperceptions, especially concerning its mode of action, impact on behaviour and safety. EC pills prevent pregnancy by inhibiting or delaying ovulation, but they cannot disrupt an established pregnancy. However, an analysis of 1 077 articles in 113 newspapers between 1992 and 2002 showed that 44.5% of them included at least one instance of confusion between EC and medical abortion, with 31.0% of the articles inaccurately portraying the mode of action of EC as medical abortion.[6] The use of EC varies in different countries, and o...