Knowledge and Awareness of Familial Hypercholesterolaemia among Registered Medical Practitioners in Tamil Nadu: Are They Suboptimal?

Rangarajan, Nandhini; Shanthi, B.; Pang, Jing; Watts, Gerald F.

doi:10.7860/jcdr/2016/18798.7893

Cited by 14 publications

(33 citation statements)

References 16 publications

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“…Moreover, this study revealed substantial deficits in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of new, non-statin medications for FH, such as PCSK9 inhibitors. Our findings are consistent with previous studies [ 20 – 23 ].…”

Section: Discussionsupporting

confidence: 94%

“…Opportunistic screening by general practitioners (GPs) could address the low reporting of FH and subsequently improve the patient outcome [ 7 , 16 – 18 ]. Around 92% of the lipid profiles in the community were requested by GPs, confirming that they play an essential role in detecting individuals with FH [ 19 ]; however, several studies have found physicians' knowledge and awareness of FH to be suboptimal [ 20 – 23 ]. The knowledge and awareness of FH between varying specialties (primary care physicians (PCP) versus specialists) was not significantly different, except that about two- thirds of PCPs selected themselves as the best health providers for detecting FH and subsequent screening of the first-degree relatives [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Assessment of physicians’ awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?

et al. 2017

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BackgroundThe scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians.ObjectiveTo assess physicians’ awareness, practice, and knowledge of FH in Saudi Arabia.MethodsThis is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire.ResultsA total of 294 physicians completed the survey (response rate 90.1%). Overall, 92.9% of the participants have poor knowledge of FH while only 7.1% have acceptable knowledge. The majority (68.7%) of physicians rated their familiarity with FH as average or above average, and these had higher mean knowledge scores than participants with self-reported below average familiarity (mean 3.4 versus 2.6) (P < 0.001). Consultant physicians were 4.2 times more likely to be familiar with FH than residents or registrars (OR = 4.2, 95% CI = 1.9–9.1, P < 0.001). Physicians who currently managed FH patients had higher mean knowledge scores compared to those without FH patients in their care (3.5 versus 2.9) (P = 0.006). In addition, there were statistically significant differences between physicians’ mean knowledge scores and their ages, levels of training, and years in practice. Moreover, a substantial deficit was identified in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of statin alternatives, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.ConclusionA substantial deficit was found in the awareness, knowledge, practice, and detection of FH among physicians in Saudi Arabia. Extensive educational programs are required to raise physician awareness and implement best practices; only then can the impact of these interventions on FH management and patient outcome be assessed.

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Section: Discussionsupporting

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Assessment of physicians’ awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?

et al. 2017

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“…1 which assessed FH familiarity, Likert scale scores of 1 to 4 were interpreted as 'unfamiliar' and coded as '0' while scores of 5 to 7 were interpreted as 'familiar' and coded as '1'. The interpretation was done in accordance to the study by Rangarajan et al [23] and Pang et al [25]. For all of the items that have predetermined correct answers, incorrect response was coded as '0' while correct response was coded as '1'.…”

Section: Questionnaire Interpretation Coding and Scoringmentioning

confidence: 99%

“…Numerous studies have shown that there were gaps in knowledge, awareness and practice (KAP) regarding FH among PCP in various parts of the world [18][19][20][21][22][23][24][25], especially in developing countries [25].…”

Section: Introductionmentioning

confidence: 99%

“…This questionnaire was initially developed with the aim to determine the KAP regarding FH among PCP in Western Australia [18]. Since then, this questionnaire has been validated and tested in several populations including the UK [21,22], India [23] and Saudi Arabia [24]. Although the FH 'Ten Countries Study' already included 219 Malaysian PCP [25], little is known regarding the gaps in KAP between PCP with PG qualification and those without.…”

Section: Introductionmentioning

confidence: 99%

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Adaptation and validation of a questionnaire measuring knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia

Azraii

Ramli

Ismail

et al. 2019

Preprint

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Background: Primary care physicians (PCP) play an important role in early detection of Familial Hypercholesterolaemia (FH). However, knowledge, awareness and practice (KAP) regarding FH among Malaysian PCP are not well established, and there was no validated tool to assess their FH KAP. Therefore, this study aimed to adapt an FH KAP questionnaire and to determine its validity and reliability among Malaysian PCP. Methods: This cross-sectional validation study involved PCP with ≥1-year working experience in the Malaysian primary care settings. In Phase 1, the original 19-item FH KAP questionnaire was content validated and adapted by 7 experts. The questionnaire was then converted into an online survey instrument and was face validated by 10 PCP. In Phase 2, the adapted questionnaire was distributed via e-mail to 1500 PCP for self-administration. Data were collected on their KAP, demography, qualification and work experience. The construct validity was tested using known-groups validation method. PCP with postgraduate qualification (PCP-PG-Qual) were hypothesized to have better FH KAP compared with PCP without postgraduate qualification (PCP-noPG-Qual). The internal consistency reliability was tested using Kuder Richardson formula-20 (KR-20) and test-retest reliability was tested on 26 PCP using kappa statistics. Results: During content validation and adaptation, 10 items remained unchanged, 8 items were modified, 1 item was moved to demography and 7 items were added. The adapted questionnaire contained 25 items (11 knowledge, 5 awareness and 9 practice items). A total of 130 out of 1500 PCP (response rate: 8.7%) completed the questionnaire. The mean percentage knowledge score was significantly higher in PCP-PG-Qual compared to PCP-noPG-Qual (53.5, SD±13.9 vs. 35.9, SD±11.79), t(128)=6.90, p<0.001. The median percentage awareness score was significantly higher in PCP-PG-Qual compared to PCP-noPG-Qual (15.4, IqR±23.08 vs. 7.7, IqR±15.38), p=0.030. The mean percentage practice score was significantly higher in PCP-PG-Qual compared to PCP-noPG-Qual (69.2, SD±17.62 vs. 54.4, SD±19.28), t(128)=3.79, p<0.001. The KR-20 was 0.79 (moderate reliability) and average Kappa was 0.796 (substantial agreement). Conclusion: The robust validation methods and findings suggest that the adapted 25-item questionnaire is a valid and reliable tool to measure FH KAP among Malaysian PCP. This would aid to improve FH care in the community.

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Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

et al. 2018

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The EAS FHSC is an international initiative involving a network of investigators interested in FH from around 70 countries.• Information on FH prevalence is lacking in most countries; where available, data tend to align with contemporary estimates.• FH diagnosis and management varies widely across countries, with overall suboptimal identification and under-treatment.• In most countries diagnosis primarily relies on DLCN criteria, and less frequently on Simon Broom or MEDPED.• Therapy for FH is not universally reimbursed, and criteria vary across countries. Access to PCSK9i and apheresis is limited.

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Knowledge and Awareness of Familial Hypercholesterolaemia among Registered Medical Practitioners in Tamil Nadu: Are They Suboptimal?

Cited by 14 publications

References 16 publications

Assessment of physicians’ awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?

Assessment of physicians’ awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?

Adaptation and validation of a questionnaire measuring knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia

Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

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