Knowledge and Awareness of Peripheral Vascular Disease Are Poor Among Women at Risk for Cardiovascular Disease

Bush, Ruth L.; Kallen, Michael A.; Liles, Debra R.; Bates, Jeffrey T.; Petersen, Laura A.

doi:10.1016/j.jss.2007.03.022

Cited by 30 publications

(25 citation statements)

References 37 publications

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“…Moreover, populations at highest risk for PAD, such as the elderly and minorities, were the least informed. A Canadian survey provided similar results – two of three adult Canadians were unaware of PAD39 – whereas Bush et al reported that PAD knowledge was poor among women at risk for cardiovascular diseases 40…”

Section: Challenges Associated With Diagnostic Aspects Of Pad In Womenmentioning

confidence: 90%

Challenges associated with peripheral arterial disease in women

Barochiner¹,

Aparicio²,

Waisman³

2014

VHRM

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Peripheral arterial disease (PAD) is an increasingly recognized disorder that is associated with functional impairment, quality-of-life deterioration, increased risk of cardiovascular ischemic events, and increased risk of total and cardiovascular mortality. Although earlier studies suggested that PAD was more common in men, recent reports based on more sensitive tests have shown that the prevalence of PAD in women is at least the same as in men, if not higher. PAD tends to present itself asymptomatically or with atypical symptoms more frequently in women than in men, and is associated with comorbidities or situations particularly or exclusively found in the female sex, such as osteoporosis, hypothyroidism, the use of oral contraceptives, and a history of complications during pregnancy. Fat-distribution patterns and differential vascular characteristics in women may influence the interpretation of diagnostic methods, whereas sex-related vulnerability to drugs typically used in subjects with PAD, differences in risk-factor distribution among sexes, and distinct responses to revascularization procedures in men and women must be taken into account for proper disease management. All these issues pose important challenges associated with PAD in women. Of note, this group has classically been underrepresented in research studies. As a consequence, several sex-related challenges regarding diagnosis and management issues should be acknowledged, and research gaps should be addressed in order to successfully deal with this major health issue.

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Section: Challenges Associated With Diagnostic Aspects Of Pad In Womenmentioning

confidence: 90%

Challenges associated with peripheral arterial disease in women

Barochiner¹,

Aparicio²,

Waisman³

2014

VHRM

View full text Add to dashboard Cite

show abstract

“…15 It is unclear whether knowledge deficit or lack of screening for PAD in women contributes to their presentation with more advanced arterial occlusive disease. 16,17 Although PAD is a known manifestation of systemic atherosclerosis and is associated with cardiovascular morbidity and mortality, 18 it continues to be underdiagnosed in primary care clinics. Hirsch et al evaluated 6979 patients aged 70 years and older or aged 50 to 69 who had a history of smoking or diabetes mellitus.…”

Section: Discussionmentioning

confidence: 99%

Do Women Have Worse Amputation-Free Survival Than Men Following Endovascular Procedures for Peripheral Arterial Disease? An Evaluation of the California State-Wide Database

Hedayati

Brunson

et al. 2015

Vasc Endovascular Surg

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Objectives: Female gender has been shown to negatively affect the outcomes of surgical bypass for peripheral arterial disease (PAD). We examined gender-related disparities in outcomes of endovascular PAD procedures in a large population-based study. Methods: We used discharge data from California hospitals to identify patients who had PAD interventions during 2005 to 2009. Logistic regression was used for 12-month reintervention, and Cox proportional hazard regression was used for amputation-free survival comparisons. Results: A total of 25 635 patients had endovascular procedures (11 389 [44.4%] women). Women were more likely than men (34.5% vs 30.1%, P < .0001) to have critical limb ischemia (CLI). Twelve-month reintervention rate in women was similar to men. Amputation-free survival was better among women than men (hazard ratio 0.84, 95% confidence interval [CI] 0.76-0.93, P ¼ .0006). Conclusion: Despite presenting more frequently with CLI, women had better amputation-free survival than men following endovascular procedures. Future research should determine whether findings favor one type of PAD treatment modality over another for women.

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“…A cross-sectional study by Bush et al 296 that focused on 162 women from a Veterans Affairs ambulatory clinic reported that PAD knowledge and awareness were poor among women at risk for CVD (Table 4). Data were collected by use of a self-reported questionnaire that focused on symptoms, perceived risk factors, and patient preferences for knowledge.…”

Section: Awareness and Knowledge Of Pad Among Womenmentioning

confidence: 99%