Knowledge and medication adherence of oral anticoagulant-taking patients in Vietnam

Tran, Minh-Hoang; Nguyen, Hoang Hai; Khanh, Quoc; Pham, Hong Tham

doi:10.1016/j.rpth.2023.100044

Cited by 6 publications

(7 citation statements)

References 17 publications

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“…[ 82 ] In Vietnam, this problem is particularly pronounced, given that only approximately one-third of patients have good adherence to anticoagulation therapy. [ 83 ] It is crucial to emphasise that patients can benefit from stroke prevention only as long as they maintain regular anticoagulant use. Thus, regardless of the specific anticoagulant selected for a patient, adherence plays a pivotal role in achieving favourable treatment outcomes.…”

Section: Discussion and Expert Opinionmentioning

confidence: 99%

“…Global and local concerns regarding low public awareness of AF and anticoagulants persist. [ 83 , 84 ] In Vietnam, public education programmes have been initiated, including the launch of dedicated websites by the Vietnamese Ministry of Health Stroke Free Program, to promote stroke prevention among patients. [ 85 ] However, there remains a need for more active and widespread implementation of patient education programmes.…”

Section: Discussion and Expert Opinionmentioning

confidence: 99%

See 1 more Smart Citation

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2

Ton,

Ho,

Nguyen

et al. 2023

Eur Cardiol

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Part 1 of this review provided an overview of AF in Vietnam, with a particular focus on primary and secondary stroke prevention. Part 2 explores the management of AF in special, high-risk and clinically common patient populations including those with renal impairment, diabetes, the elderly, and those with coronary artery disease. Furthermore, Part 2 addresses the challenges posed by patients with AF who have a bioprosthetic valve, a group situated in a grey area of consideration. Managing AF in these patient groups presents unique clinical challenges that require careful consideration. Physicians are tasked with addressing specific clinical questions to identify the optimal anticoagulation strategy for each individual. To inform these decisions, subgroup analyses from pivotal studies are presented alongside real-world data derived from clinical practice. By synthesising available information and considering the nuanced clinical context, the aim is to provide informed perspectives that align with current medical knowledge and contribute to the enhancement of patient care in these challenging scenarios.

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Section: Discussion and Expert Opinionmentioning

confidence: 99%

Section: Discussion and Expert Opinionmentioning

confidence: 99%

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2

Ton,

Ho,

Nguyen

et al. 2023

Eur Cardiol

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“…The ease of use is an important issue for our study population who had low‐health literacy. In addition, it has been previously tested in the Vietnamese population with good results 25 . MGL consists of questions that address barriers to medication‐taking and allow the healthcare provider to reinforce positive adherence behaviors.…”

Section: Methodsmentioning

confidence: 99%

“…In addition, it has been previously tested in the Vietnamese population with good results. 25 MGL consists of questions that address barriers to medication-taking and allow the healthcare provider to reinforce positive adherence behaviors. Total MGL scores can range from 0 to 4 and can be categorized into three levels of adherence: low (0-1), moderate (2,3), and high (4) adherence.…”

Section: Hypertension Knowledge-level Scale and Morisky Green Levine ...mentioning

confidence: 99%

Effect of pharmacist‐led interventions on hypertension‐related knowledge, medication adherence, and blood pressure control: A multi‐center, randomized, controlled trial in Vietnam

Huynh,

Vo,

Pham

et al. 2024

J Am Coll Clin Pharm

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IntroductionHypertension is the single most important leading cause of morbidity and mortality in the Vietnamese population and remains poorly controlled by the current conventional care model.ObjectivesTo evaluate whether pharmacist‐led interventions can improve hypertension knowledge, medication adherence, and blood pressure (BP) control in Vietnamese patients with hypertension.MethodsA multi‐center, randomized, controlled trial was conducted in three hospitals in Vietnam from October 2021 to May 2022. The educational interventions included direct counseling, printed material, and educational videos for smartphones. The primary outcome was hypertension knowledge assessed by the Hypertension Knowledge‐Level Scale (HK–LS). Secondary outcomes were medication adherence as assessed by the Morisky Green Levine Adherence Scale (MGL) and changes in systolic (SBP) and diastolic BP (DBP) at week 12.ResultsA total of 381 patients were included in the study, with 190 and 191 patients in the intervention and control groups, respectively. At week 12, patients in the intervention group had a significantly higher mean HK–LS than the control group (18.97 ± standard deviation [SD] 2.10 vs. 14.98 ± SD 3.55, respectively; p < 0.001). Significantly higher medication adherence was observed in the intervention group than in the control group (MGL score of 3.76 ± 0.52 vs. 3.20 ± 0.87, respectively; p < 0.001). Patients in the intervention group had a significant reduction in mean SBP/DBP (−6.15/−2.58 mmHg) compared with the control group (−0.98/−0.92 mmHg; p < 0.001).ConclusionPharmacist‐led interventions resulted in a significant improvement in disease knowledge, medication adherence, and BP control in the Vietnamese context of practice and health system.

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“…Another study conducted in Hong Kong by Tang et al found a positive correlation between patients' knowledge of warfarin and the number of international normalized ratio (INR) values within the target range [ 11 ]. A Vietnamese study also demonstrated a strong association between patients' knowledge and treatment adherence in patients taking DOACs [ 12 ]. The findings from these studies suggest that an adequate knowledge of anticoagulants may lead to better clinical outcomes and may reduce the risk of adverse events.…”

Section: Introductionmentioning

confidence: 99%

Development and validation of the Chinese oral anticoagulants knowledge tool (C-OAKT): A pilot study

Chan,

Sin,

Lee

et al. 2023

PEC Innovation

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Knowledge and medication adherence of oral anticoagulant-taking patients in Vietnam

Cited by 6 publications

References 17 publications

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2

Effect of pharmacist‐led interventions on hypertension‐related knowledge, medication adherence, and blood pressure control: A multi‐center, randomized, controlled trial in Vietnam

Development and validation of the Chinese oral anticoagulants knowledge tool (C-OAKT): A pilot study

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