This research on Lassa fever was conducted in rural communities located within Oke-Ero Local Government Area of Kwara State. We use multi-stage sampling technique consisting of simple random, proportionate and convenience sampling techniques to select a sample size of (402) respondents for this study. The results of the study among the respondents showed that abortion and haemorrhage are significantly perceived as implications of LF as cal. χ2 (256.69) was greater than the critical value (16.92) and cal. χ2 (238.597) was greater than the critical value (16.92) at degree of freedom 9 and α=0.05 for the latter and former respectively. Other results revealed that the residents of Oke-Ero LGA significantly have knowledge of causes, prevention and symptoms of LF as cal. χ2 (1011.28) was greater than the critical value (7.82), cal. χ2 (668.299) was greater than the critical value (7.82); and cal. χ2 (437.79) was greater than the critical value (7.82) for the three cases at DF 3 and α=0.05 respectively. From the findings the null hypotheses were rejected in all cases. These results showcase positive correlation with the level of education of the respondents. In conclusion, the residents of Oke-Ero LGA have knowledge of causes, prevention and symptoms of LF and they perceived abortion and haemorrhage as implication of LF. Therefore, the researchers recommend that government at all levels, further strengthen campaigns on the causes, symptoms, and prevention of LF and encourage community participation in health education and environmental sanitation.