The 2021 virtual issue of the Health Information and Libraries Journal is published to link to the Future Technologies Conference 2021, which takes place in Vancouver, Canada, 28-29 October 2021. This event, which began in 2016, presents the best of current systems research and practice. One of the themes of the 2021 conference is Smart Healthcare. Although libraries may appear to be far removed from some of the breakthroughs reported in the Future Technologies Conference, what is clear is that unlike those who work with technology, librarians work closely with the end users of health information-clinicians, managers, students, patients and the general public. The articles included in this virtual issue provide important insights into what library user groups want and what does and does not meet their needs.