Knowledge, attitude, and practices of health-care providers toward antibiotic prescribing, antibiotic resistance, and multidrug-resistant tuberculosis

Abstract

Introduction: Antibiotic resistance (ABR) is a growing public health problem and is a subject of international concern. It poses a serious threat to health and health-care systems in both developed and developing countries. The problem is more confounding with tuberculosis (TB), and drug resistance in TB has threatened the progress made in TB care and control worldwide. The aim of this study was to understand the knowledge, attitude, and practices of health-care providers (HCPs) toward antibiotics, antibiotic prescribing, ABR, and multidrug-resistant TB (MDR-TB). Materials and Methods: A total of 125 participants were included in this cross-sectional, questionnaire-based survey conducted in tertiary care teaching hospitals of the Delhi-NCR region. A five-point Likert scale, whose responses ranged from “strongly agree” to “do not know,” was used to record the responses from participants. Results: Among the 125 HCPs who participated in the survey, the response rate was 100%. Around 94.4% of the respondents agreed that ABR is an important and a serious public health issue. More than 80% of the respondents strongly agreed that over-the-counter sale and/or dispensing antibiotics without prescription should be controlled. About 86.4% of the participants agreed that MDR-TB is a growing problem and 59.2% strongly agreed that indiscriminate use of anti-TB drugs could be a major causative factor. Almost 85.6% of the participants agreed that a proper diagnosis should be ensured before treating the TB cases. Conclusions: HCPs had a good knowledge of antibiotics and the association of its misuse or overuse with increasing ABR. Educational and persuasive measures are certainly needed, but the use of restrictive and organizational measures appears mandatory if the misuse of antibiotics is to be decreased in the near future. A stringent assessment of the impact of implemented measures seems essential to better guide antibiotic stewardship in our country.

Knowledge, Attitude, and Practices Among Healthcare Practitioners in the Context of Multidrug Resistance Tuberculosis: An Appraisal to Disease Elimination

“…A large number of practitioners (80.8%) admit to having encountered MDR-TB in their clinical practice and the majority (95.2%) of the health care practitioners (HCPs) believe MDR-TB is a rising problem. Another study also reported that antibacterial resistance in the treatment of TB is an important and increasing public health problem [ 9 ].…”

“…These knowledge gaps regarding MDR-TB were also identified by other studies. In one study, the authors reported that 59.2% of their study participants strongly agreed that the indiscriminate use of anti-TB drugs could be a major factor attributing to MDR-TB [ 9 ]. This could be due to the fact that most of the sensitization and training programs in our country are held in the government settings, but in a high burden country like India, the training programs should be robust and rigorous and should be conducted in every setting (both private and government) on a regular basis to achieve the ultimate goal of TB elimination by 2025 [ 3 ].…”

Tingkat Pengetahuan Dan Sikap Orang Tua terhadap Pemakaian Antibiotik pada Anak di RSUD Abepura

“…Perolehan pengkajian ini selaras pada Chan, dkk di Malaysia yang mengatakan bila "ibu yang memiliki tingkat pengetahuan dan sikap rendah, menunjukkan tingkat perilaku rendah juga" (15). Tindakan edukasi dan persuasif tentu saja diperlukan, tetapi penggunaan tindakan restriktif dan terorganisir tampaknya wajib dilakukan jika penyalahgunaan antibiotik ingin dikurangi dalam waktu dekat (19). Penting untuk memahami hubungan antara penggunaan antibiotik dan resistensi bakteri untuk membantu merumuskan kebijakan dan praktik penggunaan antibiotik yang lebih bijaksana (20).…”

Knowledge, Attitude, and Practices of Mothers Working as Nurses Toward Multidrug-Resistant: Impact of an Educational Program in Neonatal Intensive Care Unit

“…22 Inappropriate antibiotic usage is influenced by various factors that contribute to the misuse and overuse of these medications in addition to one significant factor that is physicians’ nonadherence to treatment guidelines, which may stem from a lack of awareness or disregard for established protocols, so the nurse’s role is to adhere to the physician to follow the protocol. 23 Additionally, insufficient knowledge of MDROs (nurses) plays a role in this global problem. Fear of clinical failure and external pressures, such as influence from patient demands for antibiotics regardless of necessity, also contribute to the problem.…”

“…Fear of clinical failure and external pressures, such as influence from patient demands for antibiotics regardless of necessity, also contribute to the problem. Furthermore, self-prescribing exacerbates the issue by bypassing professional medical guidance, and all of these challenges addressed by Malhotra et al 23 were found to contribute to antibiotic resistance. It is crucial to provide guidelines and timely, comprehensive information to address this concern and this needs an educational program.…”