Nursing students are the essential part of the healthcare system all over the world, and play a significant role in the nursing job in the future. In crises, such as the present one, nursing students’ knowledge, attitudes and practices toward COVID-19 prevention should be considered in the planning for health promotion and disease control especially effective educational implementations for COVID-19. The aim of study to assess the attitude and practice regarding COVID 19 prevention and associate their relation with socio- demographic characteristics of nursing college students. The result of the present study showed that nursing students had a favorable attitude (75.6%), and moderate level of practices (62, 6%) toward COVID-19 prevention.