Introduction:The huge workload on doctors especially residents, who are the main healthcare providers in public hospitals, in addition to the vanishing incomes and lack of personal safety during the decade-long Syrian crisis, led to further hurdles for the focus on research. Postgraduate students in the medical and paramedical fields must conduct original research projects as part of their graduation requirements. However, that does not reflect on the research publications coming from Syria.Methods:A nation-wide cross-sectional study targeting medical, dental, and pharmacy postgraduate students who are at the phase of planning for their required projects. The questionnaire aimed to capture their attitudes towards research, perceived barriers, and previous research experiences.Results:The sample consisted of 429 residents representing about 21.5% of the target population. Nearly all the participants had positive opinion towards the important role of medical research and the significance of their participation. Agreement was also clear regarding perceived barriers including the lack of adequate training, and research facility. Seventy-one percent of the participants were not involved in any research before the time of their master theses, less than 13% of them had submitted an article for publication, and less than 5% had submitted more than one paper. Poor internet connectivity and poor reading and writing English skills were decisive negative factors in previous research experiences. Active mentors’ support and self-paced education on research skills had a significant positive impact on students’ research contributions with odds ratios of 2.24 [1.34-3.74] (P=0.003) and 2.28 [1.47-3.52] (P<0.001) respectively.Conclusion:The attitudes of postgraduate students towards research were quite positive but hindered by several obstacles. Further integration of research practical training in the curriculums, allowing long-distance mentoring, enhancing collaboration between peers, as well as narrowing the distance between students and mentors may significantly boost research productivity in Syria despite the conflicts.