Knowledge, attitudes and practices of nurses and pharmacists towards adverse drug reaction reporting in the South African private hospital sector

Bogolubova, Sophia; Padayachee, Neelaveni; Schellack, Natalie

doi:10.4102/hsag.v23i0.1064

Cited by 17 publications

(17 citation statements)

References 19 publications

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“…40,41 Only 95 (31.7%) respondents in this study had some form of training on ADR reporting similar to reports from South Africa and Saudi Arabia with 76.2% and 76.3% of the respondents had no training. 24,38 Adverse drug reaction reports are usually collated and processed at the national pharmacovigilance center for each country. Majority (194; 64.7%) of participants in our study knew of the national pharmacovigilance center in Nigeria, an outcome similar to reports from studies conducted among HCPs in Nepal and Ethiopia.…”

Section: Discussionmentioning

confidence: 99%

“…21 Other reasons enumerated in studies conducted in LMICs include lack of training in ADR reporting, not being aware of the appropriate authority to report to, poor feedback from national reporting centers and lack of incentives. 22-25 In Nigeria, the procedure for reporting of ADRs starts from the HPCs who document the observed or reported ADR using the yellow card. The yellow card is an ADR reporting form which was developed in the United Kingdom and is used widely for ADR reporting worldwide.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting Among Healthcare Professionals working in Primary, Secondary and Tertiary Healthcare Facilities in Ekiti State, South-West Nigeria

et al. 2020

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Background: Adverse drug reactions (ADRs) constitute a significant global healthcare challenge associated with increased morbidity, mortality and healthcare costs; however, there are concerns that ADRs are grossly under-reported by different categories of healthcare professionals (HCPs) in many countries. The main objective of this study was to assess the knowledge, attitude and practice of ADR reporting of HCPs working at the primary, secondary and tertiary levels of care in Ekiti State, Nigeria. Methodology: This was a self-administered questionnaire-based study conducted among HCPs working in Ekiti State, South-west Nigeria. The questionnaire which was adapted from ones used in similar studies was reviewed for content validity by experts in the field. Healthcare professionals (medical doctors, pharmacists, nurses, community health extension workers, and other allied HCPs) working in the 3 tiers of healthcare participated in the study. The questionnaire consisted of sections on the demographics of respondents, their knowledge, attitude and practice of ADR reporting. Data analysis was done using SPSS (version 25) employing t test, ANOVA and chi-square as appropriate with P-value < .05 accepted as being statistically significant. Results: Three hundred HCPs comprising of nurses (112; 37.3%), physicians (75; 25.0%), pharmacists (53; 17.7%), community health extension workers (40; 13.3%) and others (20; 6.7%) completed the questionnaire with 166 (55.3%) of them working in tertiary healthcare facilities. Male respondents (6.3 ± 1.7; P = .003), pharmacists (7.0 ± 1.6; P < .0001), HCPs and those from tertiary centers (6.2 ± 1.7; P = .028) had higher knowledge scores. While 228 (76%) respondents had observed incidents of ADR during their professional practice, only 75 (25%) have ever reported it. Only 113 (37.7%) of respondents had seen the adverse drug reaction reporting form with only 53 (17.7%) ever using it. The reporting methods preferred by respondents were through email/internet (102; 34.0%), phone/SMS (78; 26.0%) and using the hard copy of the forms (95; 31.7%). The attitude of respondents towards ADR reporting was mainly positive. Conclusion: There was significant variation in the knowledge of different categories of HCPs and facility levels about ADR reporting. Encouragingly, the overall attitude of respondents towards ADR reporting was positive. Based on the above, strategies are needed to build capacity of HCPs in the area of on adverse drug reaction and its’ reporting.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessment of Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting Among Healthcare Professionals working in Primary, Secondary and Tertiary Healthcare Facilities in Ekiti State, South-West Nigeria

et al. 2020

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“… Data can be used to demonstrate the need for health promotion activities that should focus on the direct effects of smoking and caffeine consumption. An issue of great importance is the fact that there is still a need for regulations/guidelines concerning public health and especially young people [ 1 , 2 ]. Communication of such policies should be done by employing contemporary approaches [ 3 , 4 ].…”

mentioning

confidence: 99%

“…An issue of great importance is the fact that there is still a need for regulations/guidelines concerning public health and especially young people [ 1 , 2 ]. Communication of such policies should be done by employing contemporary approaches [ 3 , 4 ].…”

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confidence: 99%

Data on advanced glycation end-products concentrations and haemodynamic parameters following caffeine and nicotine consumption in nursing students

et al. 2020

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This work presents data from a non-invasive interventional trial investigating the early effects of caffeine and nicotine on both the concentrations of advanced glycation end-products (AGEs) and haemodynamic parameters in 178 healthy nursing students aged between 18 and 40. These students were allocated into four groups (A, B, C and D) and the concentrations of AGEs as well as haemodynamic parameters were measured non-invasively using the AgeReader and the Finometer devices, respectively. The haemodynamic parameters that were measured included systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, inter-beat interval, stroke volume, cardiac output, ventricular ejection time, total peripheral resistance, ascending aorta impedance and total arterial compliance. According to our protocol, each beverage contained 100 mg of caffeine each cigarette contained 1.5 mg of nicotine. The present data reveal the combined effect of smoke and caffeine consumption to several hemodynamic parameters that may be related to the onset of elevated blood pressure during smoking and following caffeine consumption.

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“…All studies were published in English from 2010 to 2020. Four studies were from India [ 28 – 31 ], three from South Africa [ 32 – 34 ], three from Turkey [ 35 – 37 ], two from Saudi Arabia [ 38 , 39 ], two from Jordan [ 40 , 41 ], two from Pakistan [ 42 , 43 ], two from Nepal [ 44 , 45 ], one from Bhutan [ 46 ], one from Sweden [ 47 ], one from Iran [ 48 ], one from the United Arab Emirates [ 49 ], and one from Ethiopia [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Nurses’ Knowledge, Attitudes, and Practice in Relation to Pharmacovigilance and Adverse Drug Reaction Reporting: A Systematic Review

Salehi

Seyedfatemi

Mirzaee

et al. 2021

BioMed Research International

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Aim. To describe and synthesize aspects of knowledge, attitudes, and practice regarding pharmacovigilance and adverse drug reaction (ADR) reporting and to explore associated barriers from a nurse perspective. Methods. A systematic review was conducted. Electronic databases including MEDLINE, Embase, Scopus, and Web of Knowledge from January 2010 to October 2020 were searched. Original observational studies that were written in English and which focused on nurses’ knowledge, attitudes, practice, and perceived barriers regarding pharmacovigilance and ADR reporting in various healthcare settings were included. Results. Twenty-three studies published in English from 2010 to 2020 were retrieved during the search process. Overall, in the knowledge domain, the median percentages of nurses who were aware of the definitions of ADRs were 74.1%, while only 26.3% were aware of the adverse drug reaction reporting form. In the attitude domain, 84.6% of nurses believed ADR reporting to be important for patient/medicine safety and 37.1% had a fear of legal liability following ADR reporting. Although 67.1% of nurses encountered ADRs during their professional life, only 21.2% had a history of ADR reporting. In addition, lack of knowledge/training (median: 47.1%) was identified as the most common barrier in ADR reporting from a nursing viewpoint. Conclusion. Despite positive nurse attitudes, knowledge and practice in relation to pharmacovigilance activities and ADR reporting did not occur regularly or often. Improving nurses’ knowledge through in-service training and degree-level education and addressing the main barriers of ADR reporting may help to achieve an improved level of reporting.

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Knowledge, attitudes and practices of nurses and pharmacists towards adverse drug reaction reporting in the South African private hospital sector

Abstract: practices of nurses and pharmacists towards adverse drug reaction reporting in the South African private hospital sector', Health SA Gesondheid 23(0), a1064.

Cited by 17 publications

References 19 publications

Assessment of Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting Among Healthcare Professionals working in Primary, Secondary and Tertiary Healthcare Facilities in Ekiti State, South-West Nigeria

Assessment of Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting Among Healthcare Professionals working in Primary, Secondary and Tertiary Healthcare Facilities in Ekiti State, South-West Nigeria

Data on advanced glycation end-products concentrations and haemodynamic parameters following caffeine and nicotine consumption in nursing students

Nurses’ Knowledge, Attitudes, and Practice in Relation to Pharmacovigilance and Adverse Drug Reaction Reporting: A Systematic Review

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