Background and Aims: The aim of this study was to evaluate the relationship between high air temperatures and occupational injuries (OIs) occurred in construction workers (.e. 3 or more consecutive days with Tmax > 35°C). Daily average temperatures (Tday) were then categorized in 7 exposure groups (<5th, 5-9th, 10-24th, 25-74th, 75-89th, 90-94th and ≥ 95th percentiles). The risk of OIs was assessed as odds ratio (OR) calculated through a Poisson regression model. Results: Estimated incidence of OIs during the study period was 6.2 ± 3.1 events/day (2.8 injuries / 10,000 workers / day). The peak of OIs occurred during Heat-Wave time period (OR 1.200, 95%CI 1.104-1.304) on Summer days (OR 1.093, 95%CI 1.42-1.146) and in days characterized by Tday > 95th percentile (OR = 1.142,. Colder days were seemingly associated with a protective effect (OR 0.892, and OR 0.854, for Tday < 5th percentile). Younger age groups were associated with increased risk for higher exposures. Conclusions: Presented findings recommend policymakers to develop appropriate procedures and guidelines, in particular aimed to improve the compliance of younger CWs towards severe-hot daily temperatures.