Innovation that takes place in global and national economy has specific reginal manifestations. Therefore, when evaluating the efficiency of utilizing investment resources, it's necessary to consider the specifics of territorial development, which is what this research is about. The methodology is based on correlation and regression analysis. The effectiveness of the current resourcing for all the processes, including innovation, could seemingly be assessed by comparting spending and outcomes. This study uses the domestic R&D costs as the resourcing indicator. The resulting indicators are gross regional products and the monetary value of innovative goods, products, and services. The research further applies correlation and regression analysis to identify a strong correlation between the values above, which enables modeling the development of the national economy. That allows grouping the CFD regions in terms of their potential response to domestic R&D spending, which manifests itself as a change in GRP and in the value of innovative goods.