Knowledge Mapping of Exosomes in Autoimmune Diseases: A Bibliometric Analysis (2002–2021)

Wu, Fengping; Gao, Jinfang; Kang, Jie; Wang, Xuexue; Niu, Qing; Liu, Jiaxi; Zhang, Liyun

doi:10.3389/fimmu.2022.939433

Cited by 80 publications

(61 citation statements)

References 127 publications

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“…Moreover, co-cited references were analyzed by VOSviewer ( Figure 6B ) to show the most influential literature. In addition, citation burst is a valuable indicator that reflects the references of interest to researchers in a particular domain in a period ( 28 ). In our study, the top 25 references with the strongest citation bursts were identified by CiteSpace and presented in Figure 6C , among which the citation burst for duration of references.…”

Section: Resultsmentioning

confidence: 99%

Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Yang

Lin

et al. 2022

Front. Immunol.

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BackgroundMacrophages significantly contributes to symptomology and structural progression of osteoarthritis (OA) and raise increasing attention in the relative research field. Recent studies have shown that tremendous progress has been made in the research of macrophages associated with osteoarthritis. However, a comprehensive bibliometric analysis is lacking in this research field. This study aimed to introduce the research status as well as hotspots and explore the field of macrophages research in OA from a bibliometric perspective.MethodsThis study collected 1481 records of macrophages associated with osteoarthritis from 1991 to 2021 in the web of science core collection (WoSCC) database. CiteSpace, VOSviewer, and R package “bibliometrix” software were used to analyze regions, institutions, journals, authors, and keywords to predict the latest trends in macrophages associated with osteoarthritis research.ResultsThe number of publications related to macrophages associated with osteoarthritis is increasing annually. China and the USA, contributing more than 44% of publications, were the main drivers for research in this field. League of European Research Universities was the most active institution and contributed the most publications. Arthritis and Rheumatism is the most popular journal in this field with the largest publications, while Osteoarthritis and Cartilage is the most co-cited journal. Koch AE was the most prolific writer, while Bondeson J was the most commonly co-cited author. “Rheumatology”, “Orthopedics”, and “Immunology” were the most widely well-represented research areas of OA associated macrophages. “Rheumatoid arthritis research”, “clinical symptoms”, “regeneration research”, “mechanism research”, “pathological features”, and “surgery research” are the primary keywords clusters in this field.ConclusionThis is the first bibliometric study comprehensively mapped out the knowledge structure and development trends in the research field of macrophages associated with osteoarthritis in recent 30 years. The results comprehensively summarize and identify the research frontiers which will provide a reference for scholars studying macrophages associated with osteoarthritis.

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Section: Resultsmentioning

confidence: 99%

Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Yang

Lin

et al. 2022

Front. Immunol.

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“…Bibliometrix R package (version 4.2.1) (https://www.bibliometrix.org) was used to conduct the bibliometric and visualized analysis. Besides, we used Bibliometrix to build the Bradford's Law diagram, publications geographic distribution maps, trend topic analysis, and the Sankey diagram [14][15] . Bibliometric software CiteSpace (version 6.1.R3) was used to draw the dual map of the journal [16][17] .…”

Section: Discussionmentioning

confidence: 99%

“…It is helpful for researchers in related fields to accurately grasp the current research trends by analyzing the publication. Recently, multiple bibliometric software tools have been developed, such as VOSviewer [12][13] , CiteSpace [14][15] , and Bibliometrix R package [16][17] . Researchers can analyze, compare, and visualize results across these tools and obtain information, including authors, countries, institutions, journals, and references in the area of interest.…”

Section: Introductionmentioning

confidence: 99%

Visual and bibliometric analysis of Chronic Rhinosinusitis and Nasal Polyps

Jiao

Liu

Yao

et al. 2023

Preprint

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Background: Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus microbiome dysbiosis. Nasal polyps (NPs) is one of the main manifestations which cause diverse clinical symptoms of CRS. We conducted a bibliometric and visual analysis of CRS and NPs articles published between 2003 and 2022 to provide researchers with the current state of research and potential directions. Method: We used a systematic search strategy to search relevant articles in the databases of the Web of Science from 2003 to 2022. VOSviewers, Bibliometrix R package, and CiteSpace were used to perform the bibliometric analysis. Results: 3,907 publications, including 3,266 “articles” and 641 “reviews” were retrieved. The USA made the highest contributions to global research, followed by China; furthermore, Northwestern University, Capital Medical University, and Sun Yat-Sen University had the highest number of publications. A total of 12,894 authors participated in this research, with the most published author being Bachert C., followed by Schleimer Robert P. and Schlosser Rodney J.. And the authors with the most co-citations were Bachert C., Fokkens W.J., and Gevaert P. 428 journals had published the articles of this research. Moreover, the journal with the most publications was the International Forum Of Allergy & Rhinology and the Journal Of Allergy And Clinical Immunology received the most citations. “Covid-19”, “biologic”, and “type 2 inflammation” were the top current research hotspots. Conclusion: The United States and Northwestern University were the leading country and institution in researching CRS and NPs. And Bachert C. is the most influential expert. The International Forum Of Allergy & Rhinology published the most articles, and the Journal Of Allergy And Clinical Immunology got the highest number of citations. Moreover, “Covid-19”, “biologic”, and “type 2 inflammation” were the trending topics.

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“…On the other hand, it was shown by experimental studies that their immunomodulatory characteristic is prominently diminished upon removing EVs from MSC-secretome. Although several subtypes of nano-vesicles are currently recognized, due to the recent bibliographic studies (2002-2021), two terms, “exosomes” and “extracellular vesicles”, are yet the most frequent keywords applied to describe the role of these cell-derived membranous nano-vesicles in autoimmune diseases ( 84 , 85 ). Despite the initial trend, it is now evidenced that the impact of EV subtypes and their versatility is so critical compared to what it inferred at first ( 86 , 87 ) and should not be underestimated during designing and performing future pre-clinical experiments and clinical trials.…”

Section: Extracellular Vesicles a New Therapeutic Paradigm For Autoim...mentioning

confidence: 99%

Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases

et al. 2023

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The conventional therapeutic approaches to treat autoimmune diseases through suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory drugs, are not adequately practical. Moreover, these regimens are associated with considerable complications. Designing tolerogenic therapeutic strategies based on stem cells, immune cells, and their extracellular vesicles (EVs) seems to open a promising path to managing autoimmune diseases’ vast burden. Mesenchymal stem/stromal cells (MSCs), dendritic cells, and regulatory T cells (Tregs) are the main cell types applied to restore a tolerogenic immune status; MSCs play a more beneficial role due to their amenable properties and extensive cross-talks with different immune cells. With existing concerns about the employment of cells, new cell-free therapeutic paradigms, such as EV-based therapies, are gaining attention in this field. Additionally, EVs’ unique properties have made them to be known as smart immunomodulators and are considered as a potential substitute for cell therapy. This review provides an overview of the advantages and disadvantages of cell-based and EV-based methods for treating autoimmune diseases. The study also presents an outlook on the future of EVs to be implemented in clinics for autoimmune patients.

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Knowledge Mapping of Exosomes in Autoimmune Diseases: A Bibliometric Analysis (2002–2021)

Cited by 80 publications

References 127 publications

Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Visual and bibliometric analysis of Chronic Rhinosinusitis and Nasal Polyps

Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases

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