Healthcare staff play important roles in fulfilling the vital functions of people, and job satisfaction should be maintained while performing these duties. By ensuring the job satisfaction of healthcare staff, quality of care, patient satisfaction, and reduction in medical errors can be achieved. It is important to determine the factors affecting the job satisfaction of healthcare staffs and to implement practises that can increase job satisfaction. In order for individuals providing health services to be satisfied with their work, managers should determine and eliminate the needs in the institution and ensure the quality of life and motivation of their employees. The aim of this review is to examine the factors affecting the job satisfaction of healthcare staff.