Knowledge of Anaesthesia Providers on Exposure to Inhalational Anaesthetic Agents in Ghana

Abstract

Background: Chronic exposure to inhaled anaesthetic agents poses an occupational hazard related to the practice of anaesthesia. Therefore, this study sought to find out the perception of anaesthesia providers on exposure to inhalational anaesthetics, evaluate their knowledge on the effects of chronic exposure and strategies to reduce chronic exposure to operating room inhalational anaesthetic agents. Method: This cross-sectional survey was conducted by administering a self-administered questionnaire to 71 anaesthesia providers in Ghana who attended the annual refresher course of the faculty of Anaesthesia, West African College of Surgeons, in 2016. Data collected were analysed and presented as frequencies and percentages. Results: Halothane and isoflurane were the most frequently used inhalational agents by the respondents. Majority (90.1%) of the respondents perceived they are exposed to inhalational anaesthetics in their working environment. Majority of the anaesthetic providers cited poorly functioning scavenging systems (28.2%) and use of paediatric Ayre's T-piece (28.2%) as sources of exposure to inhalational anaesthetics. All respondents admitted making attempts to reduce their exposure to inhalational anaesthetics. Majority of the respondents mentioned teratogenicity (77.5%) and hepatotoxicity (67.6%) as effects of chronic exposure to inhaled anaesthetic agents. Conclusion: Anaesthesia providers in Ghana perceived they are chronically exposed to inhalational anaesthetic agents in their work environment. They are aware of the sources of inhalational anaesthetic agent exposure, associated health risks and strategies required to reduce chronic exposure to inhaled anaesthetic agents.

The Toxic Effects of Occupational Exposure to Halogenated Inhalational Anesthetics

“…Results revealed a statistically significant reduction in attention, language, delayed recall, and total MOCA score in exposed subjects (Figure 1). Actually, the brain represents the prime target of inhalational anesthetics which work by magnifying the inhibitory function or reducing the excitatory transmission in brain nerve endings (Darkwa et al, 2017). Diminished synaptic density and dendritic numbers were noticed in subjects exposed to subclinical doses of halothane over a long-time span (Chen et al, 2022).…”