Introduction. The aim of this multicenter cross-sectional study was to assess the knowledge and attitudes of senior dental students in Riyadh, Saudi Arabia, regarding the management of traumatic dental injuries. Materials and Methods. A stratified random sample of fourth- and fifth-year dental students in different dental schools was given a two-part questionnaire; the first part included demographic questions, while the second part included case scenario questions related to knowledge and attitudes regarding the emergency management of concussion, crown fractures, luxation injuries, root fracture, and alveolar bone fracture. Data were statistically analysed using chi-square and ordinal logistic regression tests. The significance was set at p<0.05. Results. A total of 359 dental students participated in this study. The proportion of students from all dental schools with correct responses to each set of questions was as follows: alveolar bone fracture (78.4%), root fracture (70.1%), intrusive luxation (57.1%), complicated crown fracture (39.7%), uncomplicated crown fracture (35.5%), extrusive luxation (35%), concussion (31.1%), and lateral luxation (26.8%). The mean overall knowledge score of the participants was 3.421 ± 0.49. No statistically significant difference was found on any of the questions regarding the gender or year of study p>0.05. Conclusion. Based on the findings of this study, dental students’ knowledge of the management of traumatic dental injuries in the Riyadh region of Saudi Arabia ranges from low to moderate. Thus, there is a need to improve the knowledge of management of traumatic dental injuries among dental students.