Knowledge of prescription medications among cancer patients aged 65years and above

Si, Phebe; Koo, Khai-Nee; Poon, Dennis; Chew, Lita

doi:10.1016/j.jgo.2011.12.004

Cited by 16 publications

(15 citation statements)

References 39 publications

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“…Although previous research has shown that geriatric oncology patients lack knowledge about their medications and lack practices for safe medication use (Si, Koo, Poon, & Chew, 2012), none of the caregivers in this study reported problems with pain medication management or administration. Rather, caregivers described their own psychological pain from observing the suffering of their spouse and descriptions centered on the patients’ existential and psychological pain.…”

Section: Discussioncontrasting

confidence: 59%

Exploring Aging-Related Stress Among Older Spousal Caregivers

Wittenberg-Lyles¹,

Demiris²,

Oliver³

et al. 2014

J Gerontol Nurs

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The goal of this study was to explore aging-related stress among older spousal caregivers providing hospice care for an older adult with cancer. Cases were selected from an ongoing randomized controlled trial that involved audiorecorded visits with caregivers over four different time points. Recordings consisted of caregivers discussing caregiving problems and ways they attempted to cope. Four caregiver cases comprising 16 audiorecordings were qualitatively analyzed for aging-related stress during caregiving. Caregiving stress primarily involved the patients’ cognitive deficits. The caregiving experience also made older caregivers aware of their own aging and physical limitations, heightened self-imposed expectations to fulfill their role as spouse, and led them to consider their own mortality. This study informs development of caregiver interventions aimed at addressing the reciprocal challenge of caregiving and aging.

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Section: Discussioncontrasting

confidence: 59%

Exploring Aging-Related Stress Among Older Spousal Caregivers

Wittenberg-Lyles¹,

Demiris²,

Oliver³

et al. 2014

J Gerontol Nurs

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“…These include: Increased prevalence of multimorbidity (1–6); absence of a primary care provider able to coordinate the care of different specialists (7, 8); and increased use of alternative forms of treatments (9). Also older individuals may keep taking medications they no longer need when multiple physicians and multiple sites of care are involved (8).…”

Section: Introductionmentioning

confidence: 99%

Potential drug interactions and chemotoxicity in older patients with cancer receiving chemotherapy

Popa

Wallace

Brunello

et al. 2014

Journal of Geriatric Oncology

118

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Purpose Increased risk of drug interactions due to polypharmacy and aging-related changes in physiology among older patients with cancer is further augmented during chemotherapy. No previous studies examined potential drug interactions (PDI) from polypharmacy and their association with chemotherapy tolerance in older patients with cancer. Methods This study is a retrospective medical chart review of 244 patients aged 70+ years who received chemotherapy for solid or hematological malignancies. PDI among all drugs, supplements, and herbals taken with the first chemotherapy cycle were screened for using the Drug Interactions Facts software, which classifies PDIs into five levels of clinical significance with level 1 being the highest. Descriptive and correlative statistics were used to describe rates of PDI. The association between PDI and severe chemotoxicity was tested with logistic regressions adjusted for baseline covariates. Results A total of 769 PDI were identified in 75.4% patients. Of the 82 level 1 PDIs identified among these, 32 PDIs involved chemotherapeutics. A large proportion of the identified PDIs were of minor clinical significance. The risk of severe non-hematological toxicity almost doubled with each level 1 PDI (OR=1.94, 95% CI: 1.22–3.09), and tripled with each level 1 PDI involving chemotherapeutics (OR=3.08, 95% CI: 1.33–7.12). No association between PDI and hematological toxicity was found. Conclusions In this convenience sample of older patients with cancer receiving chemotherapy we found notable rates of PDI and a substantial adjusted impact of PDI on risk of non-hematological toxicity. These findings warrant further research to optimize chemotherapy outcomes.

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“…Si and colleagues [16] found that elderly patients failed to remember at least one of their medications, did not know precautions, could not read drug labels. Most did know doses and frequencies.…”

Section: Safetymentioning

confidence: 99%

Care of the Elderly Patient on Oral Oncolytics for Advanced Disease

Given

2016

Curr Geri Rep

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Oral oncolytics are now a common component of cancer care for older individuals with advanced cancer when a new treatment regimen is needed. Many of the solid tumors in elderly patients may respond to the oral oncolytics, however not without side effects and challenges to maintain adherence. This article describes some of the important areas to be considered when oral oncolytics are prescribed for elderly patients. A general overview of important intervention areas of focus is included.

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Knowledge of prescription medications among cancer patients aged 65years and above

Cited by 16 publications

References 39 publications

Exploring Aging-Related Stress Among Older Spousal Caregivers

Exploring Aging-Related Stress Among Older Spousal Caregivers

Potential drug interactions and chemotoxicity in older patients with cancer receiving chemotherapy

Care of the Elderly Patient on Oral Oncolytics for Advanced Disease

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