Knowledge of stroke and medication adherence among patients with recurrent stroke or transient ischemic attack in Indonesia: a multi-center, cross-sectional study

Abstract

BackgroundThere is a limited data in Indonesia regarding the stroke knowledge and medication adherence among stroke survivors.ObjectiveTo assess the level of stroke knowledge and medication adherence along with their relationship among stroke survivors.SettingTwo tertiary-care hospitals in Surabaya, East Java, Indonesia.MethodsA prospective, cross-sectional study was conducted among 215 stroke survivors. Stroke Knowledge Test and the Morisky Green Levine Adherence Scale questionnaires were used to evaluate stroke knowledge and medication adherence, respectively. Binary logistic regression was performed to assess the relationship between stroke knowledge and medication adherence.Main outcome measuresRelationship between stroke knowledge and medication adherence.ResultsA total of 215 patients with mean age of 56.34 ± 8.69 years were recruited into this study. Mean Stroke Knowledge Test score was 7.89 ± 3.38 with 76.7% had low level of stroke knowledge. Mean Morisky Green Levine Adherence Scale was 3.05 ± 1.11 with 52.1% had low to medium medication adherence. Education and duration of stroke correlated with stroke knowledge level (Spearman's correlation coefficient: 0.307, p = 0.001 and 0.128, p = 0.041, respectively). Age and disability correlated with medication adherence (Spearman's correlation coefficient: 0.169; p = 0.013 and 0.171; p = 0.012), respectively. After adjustment for covariates, stroke knowledge level was independently associated with medication adherence (adjusted OR: 4.37, 95% CI 2.00-9.53; p < 0.001).ConclusionStroke knowledge was low among Indonesian stroke survivors and independently related to medication adherence. Attempts should be made to increase stroke knowledge which may improve medication adherence among stroke survivors.

Clinical Pharmacist’s Contribution on Treatment Adherence and Quality of Life in Patients with Stroke: A prospective, controlled, clinical pharmacist led-educational study

“…Effective pharmacotherapy and optimal medication adherence are necessary to prevent secondary stroke. A recent study showed that optimal medication adherence rate is suboptimal among stroke survivors (30). Findings from our study clearly documented that clinical pharmacist-led educational intervention which include medication adherence and knowledge of stroke and medications improved medication adherence in patients with low adherence.…”

The Efficacy of Telemedicine for Secondary Prevention and Management Among Stroke Survivors: A Systematic Review and Meta-analysis

“…The study conducted by Ahmadi and Ogren was telephone-based, the study conducted by Lakshminarayan, Yan, and Sarfo used an integrated health application on the smartphone, while the study conducted by Kim used a combination of telephone, application, and messaging services [11,15,[18][19][20][21]. Studies have shown that poor self-management of stroke risk factors, low stroke knowledge, and poor adherence to medication are the potential causes of recurrent stroke [22]. The better outcome of the telemedicine intervention group is probably due to the fact that telemedicine can improve stroke risk factors management and drug compliance.…”

Association Between Patient Activation and Medication Adherence in Patients With Stroke: A Cross-Sectional Study

“…This suggests that patients who have had two or more strokes have better drug compliance. This may be because the patients' clinical outcome becomes worse after a stroke recurrence, which increases their awareness and attention to the role of drugs in secondary prevention ( 21 , 44 ). Similarly, patients with severe consequences may obtain more obvious benefits or relief from medication and are therefore more likely to receive prescription medication ( 21 ).…”