PurposeThis paper aims to explore the characteristics of knowledge diffusion of library and information science to reveal its development trend and influence on other disciplines.Design/methodology/approachBased on the ESI discipline classification, this paper measures the knowledge diffusion from the library and information science to other disciplines over the last 24 years using indicators in four dimensions: breadth, intensity, speed and theme of knowledge diffusion.FindingsThe results show that the knowledge diffusion breadth of library and information science is wide, spreading to 21 ESI disciplines; the knowledge spread mainly concentrates in four soft or applied disciplines, and yet partially inter-disciplinary, and the knowledge diffusion intensity to each ESI discipline is parabolic whose highest point is mostly in 2004–2005; the speed of spreading to the 21 ESI disciplines is faster and faster, and the articles at the highest speed of knowledge diffusion are basically published after 2005; the knowledge diffusion themes are becoming increasingly diverse, deepening and specialization over time.Originality/valueThis paper modifies the relevant indicators of knowledge diffusion and constructs a measurement framework of knowledge diffusion from four aspects: breadth, intensity, speed and theme. The research method can also be used to explore the characteristics of knowledge absorption of a discipline from other ones.