Kolon Kanserli Hastalarda Yaşam Analizi

Abstract

The aim of this study is to investigate the degree of risk and significance of prognostic and demographic factors affecting the survival of patients diagnosed with colon cancer. Material and Method:This was a retrospective study conducted by reviweing the medical records of 80 patients diagnosed with metastatic colon cancer at the Oncology Clinic at the Mustafa Kemal University between 01/2018 -01/2021. Cox regression analysis was performed to determine the prognostic and demographic factors affecting the colon cancer and Kaplan-Meier method was used to estimate the overall survival. Difference between the variable levels in terms of survival probabilities was investigated using the log-rank test. Results:The average age of the patients was 56.72 ± 12.42. The median survival time of patients with colon cancer was 48.42 months (95% confidence interval (CI)=41.97-54.87). Cox regression analysis showed that age, incident type 2 diabetes mellitus (DM), and family history of colon cancer were significantly associated with overall survival (p <0.005). Patients with colon cancer aged 50 years; patients with DM and patients with a family history of colon cancer were approximately 3 times more at risk compared to patients over 50 years; patients without DM and patients without colon cancer in the family, consecutively. Conclusion:The effect of prognostic and demographic factors affecting the survival of patients with colon cancer was evaluated. Our findings showed that age, DM and family history of colon cancer can be used to estimate the survial of patients with colon cancer. We believe that our results will help guide practitioners for the treatment of patients diagnosed with colon cancer.