Kolorektales Karzinom: Rolle bildgebender Verfahren in der Vorsorge

Mang, Thomas

doi:10.1007/s00117-018-0479-0

Cited by 4 publications

(1 citation statement)

References 70 publications

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“…17,18 In contrast, MSCT has multiple advantages for colon cancer diagnosis, including noninvasiveness, safety, and high cost-effectiveness. 25 –30 However, technical factors associated with CT examination (excessive intestinal content and colon contraction), a round or oval shape and small tumor volume, pathological factors (colon mucinous adenocarcinoma and malignant adenoma transformations), and intussusception, may all lead to a missed diagnosis. 31 Michele et al.…”

Section: Discussionmentioning

confidence: 99%

Value of multi-slice spiral computerized tomography for diagnosis of synchronous colorectal carcinoma: a retrospective study

et al. 2022

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Objective To compare the accuracy of multi-slice spiral computerized tomography (MSCT) with colonoscopy for diagnosing synchronous colorectal carcinoma (SCC). Methods We retrospectively analyzed all consecutive patients admitted to our institution with colorectal carcinoma between 19 September 2014 and 31 January 2020. Data on SCC patients who had undergone MSCT and colonoscopy were analyzed. Information on tumor location, tumor size, missed diagnosis by MSCT or colonoscopy, T stage, pathological type, and reasons for missed diagnosis was recorded and used to assess the diagnostic accuracies of MSCT and colonoscopy. Results Twenty-three cases met the inclusion criteria. MSCT plus colonoscopy had a significantly higher diagnostic accuracy (93.5%) than colonoscopy alone. There were significant differences in missed diagnosis rates of proximal cancer (34.8%) and distal cancer (4.3%) by colonoscopy. For MSCT, the missed diagnosis rate for tumors with a median long diameter of 1.25 cm (interquartile range 0.80, 1.50) was significantly lower than that for larger tumors (long diameter 4.00 cm; 3.00, 6.00). Conclusions MSCT is a valuable diagnostic tool for SCC that can effectively minimize the missed diagnosis rate of primary tumors when combined with colonoscopy.

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Section: Discussionmentioning

confidence: 99%

Value of multi-slice spiral computerized tomography for diagnosis of synchronous colorectal carcinoma: a retrospective study

et al. 2022

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Value of combined detection of IFOBT, tumor markers, and inflammatory markers in predicting occurrence of advanced colorectal adenoma

Wang¹,

Zhang²,

Zeng³

et al. 2021

WCJD

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Establishment and evaluation of a nomogram predicting risks of missed diagnoses of colorectal polyps

et al. 2022

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Background A missed diagnosis of colorectal polyps during colonoscopy may be associated with the occurrence of interval colorectal cancer. The risk factors for a missed diagnosis or a method to predict the risk of a missed diagnosis of colorectal polyps during colonoscopy remain unidentified. Methods The clinical data of patients who underwent two colonoscopies within three months at the Affiliated Hospital of North Sichuan Medical College between February 2017 and August 2019 were retrospectively reviewed. Independent risk factors for missed diagnoses were identified, and a nomogram was established to predict the risk of missed diagnoses. The prediction performance of the nomogram was evaluated using C-index and calibration curves, and its clinical application value was assessed using the Youden index and decision curve analysis. Results Independent influencing factors for missed diagnoses included age, endoscopist experience, bowel preparation, retroflected view, withdrawal time, number of polyps in the right colon, and number of polyps ≥ 6 mm. The C-index of the nomogram in the training and validation cohorts was 0.763 (95% confidence interval [CI]: 0.724 − 0.807) and 0.726 (95%CI: 0.657 − 0.794), respectively. The optimal cut-off value of the nomogram calculated using the Youden index was 152.2 points. Under the cut-off value, the sensitivity, specificity, positive predictive value, and negative predictive value were 67.1%, 75.7%, 45.8%, and 88.2%, respectively, in the training cohort, and 57.1%, 79.9%, 53.3%, and 82.3%, respectively, in the validation cohort. Conclusions The nomogram provides a reference value for clinicians to analyse the risk of a missed diagnosis of colorectal polyps in individuals, identify high-risk groups, and formulate appropriate follow-up strategies.

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Kolorektales Karzinom: Rolle bildgebender Verfahren in der Vorsorge

Cited by 4 publications

References 70 publications

Value of multi-slice spiral computerized tomography for diagnosis of synchronous colorectal carcinoma: a retrospective study

Value of multi-slice spiral computerized tomography for diagnosis of synchronous colorectal carcinoma: a retrospective study

Value of combined detection of IFOBT, tumor markers, and inflammatory markers in predicting occurrence of advanced colorectal adenoma

Establishment and evaluation of a nomogram predicting risks of missed diagnoses of colorectal polyps

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