Komfo Anokye Teaching Hospital Multidisciplinary Cleft Clinic

Agbenorku, Pius; Ansah, Samuel Kodjo; Acheampong, Alex; Sabbah, Daniel K.; Bankas, Daniel; Adu, Emmanuel J. K.; Plange‐Rhule, Gyikua; Adiyiah, Yaa; Donkor, Peter

doi:10.1097/scs.0b013e318207f462

Cited by 15 publications

(16 citation statements)

References 23 publications

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“…al , 2007). A significant side difference (more unilateral left sided clefts than unilateral right sided clefts) was reported in studies in Ghana, Nigeria and Tanzania (Carneiro and Massawe, 2009; Agbenorku et al , 2011; Butali et al , 2011). …”

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confidence: 86%

Prevalence of Orofacial Clefts in Nigeria

Butali

Adeyemo

Mossey

et al. 2014

The Cleft Palate Craniofacial Journal

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Orofacial clefts (OFC) are the most common malformations of the head and neck. In Africa, OFC is under-ascertained with little or no surveillance system in most parts for clefts and other birth defects. A Nigerian craniofacial anomalies study “NigeriaCRAN” was established in 2006 to support cleft research specifically for epidemiological studies, treatment outcomes and; studies into etiology and prevention. We pooled data from seven of the largest Smile Train treatment centers in the six geopolitical zones in Nigeria. Data from September 2006 to June 2011 were analyzed and clefts compared between sides and gender using the Fisher’s exact test. A total of 2197 cases were identified during the study period with an estimated prevalence rate of 0.5/1000. Of the total number of OFC, 53.3% are males and 47%.7 are females. There was a significant difference (p=0.0001) between unilateral left clefts and unilateral right clefts and; significant difference (p=0.0001) between bilateral clefts and either clefts on the left or right side. A significant gender difference (p=0.03) with more females than males was also observed for CP. A total of 103 (4.7 %) associated anomalies were identified, nine syndromic cleft cases and 10.4 % of the total number of clefts individuals have an affected relative. The significant difference between unilateral clefts and gender differences in the proportion of cleft palate only are consistent with the literature. The present study emphasizes the need for birth defects registries in developing countries in order to estimate the exact prevalence of birth defects including OFC.

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confidence: 86%

Prevalence of Orofacial Clefts in Nigeria

Butali

Adeyemo

Mossey

et al. 2014

The Cleft Palate Craniofacial Journal

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“…In Africa, there have been various attempts to examine the incidence, prevalence, and distribution of OFCs in different countries (Butali et al, 2014;Spritz et al, 2007;Carneiro and Massawe, 2009;Agbenorku et al, 2011;Eshete et al, 2011;Manyama et al, 2011). Here, a descriptive report of 46,502 cleft cases in the Smile Train database from all countries in sub-Saharan Africa was presented.…”

Section: Introductionmentioning

confidence: 99%

Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries

Butali¹,

PagÃ¡n-Rivera²,

Dawson³

et al. 2017

J. Public Health Epidemiol.

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“…In Ghana, OCs constitute a cause of perinatal death [13]. The survivors usually suffer from difficulties in feeding, swallowing, speaking, and hearing.…”

Section: Isrn Plastic Surgerymentioning

confidence: 99%

Incidence of Orofacial Clefts in Kumasi, Ghana

Agbenorku

Yore

Danso

et al. 2013

ISRN Plastic Surgery

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Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29.85 years (range 18–40 years). The male : female ratio for the orofacial anomalies babies was 1.3 : 1; the male : female ratio was 0.5 : 1 in the cleft lip group, 1.3 : 1 in the cleft lip and palate group, and 4 : 1 in the cleft palate group. The majority of clefts were unilateral (69.4%, n=25), with females (n=14) outnumbering males (n=11). A family history of cleft was recorded with five babies (13.9%). Associated congenital anomalies were recorded in seven (19.4%) cleft lips and/or palates. Conclusion. The incidence of 1 in 763 live births found in this study indicates that cleft lip/palate is a common congenital anomaly in Kumasi.

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Komfo Anokye Teaching Hospital Multidisciplinary Cleft Clinic

Abstract: The number of cleft surgeries was found to increase per year, and unilateral cleft lip was identified as the commonest type of cleft cases. Financial, logistic, and training support to cleft clinics in developing countries would play an essential role in the treatment of cleft patients.

Cited by 15 publications

References 23 publications

Prevalence of Orofacial Clefts in Nigeria

Prevalence of Orofacial Clefts in Nigeria

Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries

Incidence of Orofacial Clefts in Kumasi, Ghana

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