Komorbiditesi Olan COVID-19 Hastalarının Laboratuvar Bulguları, Hastanede Yatış ve Ölüm Oranlarının İncelenmesi

Acı, Recai; Keski̇n, Adem; Ari, Murat

doi:10.46237/amusbfd.971668

Cited by 3 publications

(2 citation statements)

References 23 publications

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“…It has been reported that D-Dimer values are very high in patients followed up in COVID-19 services, especially in COVID-19 patients hospitalized in intensive care units [32] . In addition, in many studies conducted with COVID-19 patients, some inflammatory indicators (C reactive protein, procalcitonin, neutrophil lymphocyte ratio and monocyte lymphocyte ratio) were found to be high [33][34][35][36] . It was stated that inflammatory, hematological and D-dimer values were also high in patients with COVID-19 with different variants [37] .…”

Section: Discussionmentioning

confidence: 99%

Co-evaluation of magnesium and 25-hydroxyvitamin D<sub>3</sub> in predicting the severity of COVID-19 disease

Keskin¹,

Acı²,

Altın³

et al. 2022

Int. J. Adv. Biochem. Res.

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The severity of COVID-19 disease ranges from asymptomatic to severe, life-threatening symptoms. The aim of our study was to co-evaluate magnesium and 25-hydroxyvitamin D3 in predicting the severity of this disease. This study included 232 inpatients with COVID-19 and 250 healthy individuals (control group). Magnesium and 25-hydroxyvitamin D3 levels were compared. ROC curve analysis was performed by co-evaluation of magnesium and 25-hydroxyvitamin D3 levels. Correlation analysis was performed between co-evaluation of magnesium and 25-hydroxyvitamin D3 levels together and the laboratory parameters used in the prognosis of COVID-19 disease. Magnesium and 25-hydroxyvitamin D3 levels of the group with COVID-19 were lower than the control group (p< 0.001). AUC value was found to be 0.924 in ROC curve analysis (p< 0.001). In the ROC curve analysis, the cut-off value for magnesium was found to be 2.20, and the cut-off value for 25hydroxyvitamin D3 was found as 25.80. Co-evaluation of magnesium and 25-hydroxyvitamin D3 levels were negatively correlated with D-dimer, C reactive protein, procalcitonin, neutrophil lymphocyte ratio and monocyte lymphocyte ratio (P< 0.05). Co-evaluation of magnesium and 25-hydroxyvitamin D3 may be useful in predicting the severity of the disease in patients with COVID-19. Low magnesium and 25-hydroxyvitamin D3 levels can be considered a risk factor in patients with COVID-19. People with magnesium and 25-hydroxyvitamin D3 deficiencies may be considered at risk for COVID-19 disease. We recommend monitoring of magnesium and 25-hydroxyvitamin D3 levels to predict the prognosis of the COVID-19 disease. Individuals may be offered prophylactic magnesium and 25-hydroxyvitamin D3 supplementation.

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Section: Discussionmentioning

confidence: 99%

Co-evaluation of magnesium and 25-hydroxyvitamin D<sub>3</sub> in predicting the severity of COVID-19 disease

Keskin¹,

Acı²,

Altın³

et al. 2022

Int. J. Adv. Biochem. Res.

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“…30 In a study investigating the effect of laboratory parameters of coronavirus patients on the duration of hospitalization, it was found that ferritin, CRP and procalcitonin levels were positively related with the day of hospitalization. 31 In a study conducted with coronavirus cases with type 2 diabetes mellitus, high levels of procalcitonin, CRP and ferritin were found. 32 Similar results were obtained in studies with different variants.…”

Section: Procalcitoninmentioning

confidence: 99%

The importance of laboratory parameters in predicting the severity of coronavirus disease-19 cases

Uzun

Birtekocak²,

Dorman

2022

Baghdad J. Biochem. Appl. Biol. Sci.

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This literature review is aimed at exploring the significance of laboratory parameters in the follow-up of the coronavirus disease-19, which is the latest global biohazard for humanity. Laboratory parameters were classified under three main headings. These headings were hematological tests, inflammatory parameters and coagulation parameters. It has been determined that low lymphocyte count, which is one of the hematological tests, is a condition seen at every stage of the disease. High neutrophil counts are evident in worsening the course of the disease. The neutrophil/lymphocyte ratio increases with increasing disease severity. Low platelet levels may also be observed. It has been determined that high C-reactive protein (CRP) levels can be seen at every stage of the disease. In addition, as the prognosis of the illness worsened, C-reactive protein levels were found to increase more. Increased prothrombin time and high D-dimer values are evident in coagulation tests in patients with severe coronavirus disease-19. In addition, increased ferritin and procalcitonin levels are observed as the illness course worsens. As a result, lymphocytopenia and increased CRP levels come to the fore in the illness course. When the illness becomes more aggressive, prothrombin time, neutrophil/lymphocyte ratio, neutrophil count, D-dimer, ferritin and procalcitonin levels draw attention.

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The Role of Some Vitamins in The Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

ARI,

UZUN,

SUGEÇTİ

2023

Caucasian Journal of Science

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a disease that entered our lives at the end of 2019 and caused a pandemic. Although it has been brought under control with the introduction of vaccines worldwide, new variants observed in the virus still remain a cause for concern. The role of some vitamins in evaluating the pathophysiological mechanisms and disease severity of this disease has been the subject of many studies. But there is no consensus. This study focused on the relationship between vitamins C, D and E and the course of SARS-CoV-2 infection. There is strong evidence showing a fairly consistent association between low vitamin D levels and poor prognosis of infection. Although there is evidence that vitamin D supplementation may play a positive role in preventing infection, there is no solid support for vitamin D supplementation in reducing the risk of complications from infection. In some clinical observations, vitamin C supplementation has been reported to improve the course of the infection. However, controlled studies have concluded that there is no statistical difference in this improvement. There is limited information on the effect of vitamin E supplementation on the course of infection. On the other hand, these patients are encouraged to take adequate amounts of antioxidant supplements such as vitamin E. Vitamins that have antioxidant properties, have an immune system regulating effect and play a role in many enzyme systems may be important in protecting against infection. It may have adjuvant effects on the course of SARS-CoV-2 infection.

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Komorbiditesi Olan COVID-19 Hastalarının Laboratuvar Bulguları, Hastanede Yatış ve Ölüm Oranlarının İncelenmesi

Cited by 3 publications

References 23 publications

Co-evaluation of magnesium and 25-hydroxyvitamin D<sub>3</sub> in predicting the severity of COVID-19 disease

Co-evaluation of magnesium and 25-hydroxyvitamin D<sub>3</sub> in predicting the severity of COVID-19 disease

The importance of laboratory parameters in predicting the severity of coronavirus disease-19 cases

The Role of Some Vitamins in The Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

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