KOMPARASI EFEK PEMBERIAN MINYAK JINTAN HITAM (Nigella sativa) DENGAN MINYAK ZAITUN (Olea europea) TERHADAP PENURUNAN GLUKOSA DARAH PADA MENCIT (Mus musculus) STRAIN Balb/c

Santoso, Setyo Dwi; Suryanto, I Wayan

doi:10.51804/jsh.v1i1.76.36-42

Cited by 4 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Oleh karena itu diperlukan pengobatan alternatif yang mekanisme kerja obat dan khasiatnya yang tidak jauh berbeda dengan obat sintetik, serta dapat meminimalisir efek samping yang ditimbulkan dari penggunaan obat sintetik. Maka salah satu pengobatan alternatif yang dapat digunakan adalah penggunaan obat tradisional dari tanaman alam (Santoso dan Suryanto, 2017).…”

Section: Pendahuluanunclassified

Formulasi Dan Uji Aktivitas Antibakteri Facial Foam Minyak Biji Jintan Hitam (Nigella Sativa Oil)

Agistia,

Novita,

Nofriyanti

2023

jppie

View full text Add to dashboard Cite

Acne is a disease that most people suffer especially among adolescent, one of the causes of acne is usually caused by the growth of acne-causing bacteria that is Staphylococcus epidermidis. One of the ingredients that can be used as an antibacterial product is black cumin seed oil (Nigella sativa oil), it is known that black cumin seed oil contains Thymoquinone and α-pinen which are efficacious as antibacterial. This research aims to produce a cosmetic preparation in the form of a face wash that effectively cleans the skin from dust and dirt from makeup, as well as preparations that have antibacterial activity against Staphylococcus epidermidis by using the well diffusion method. Black cumin seed oil is formulated into facial foam in several concentrations, namely 3% (FI), 5% (FII) and 7% (FIII). Evaluation of fa cial foam preparations includes examination of organoleptic, pH, foam power, skin irritation, homogeneity, wetting power, alcohol insoluble portion, freeze and thaw, examination of mineral oil, washability and antibacterial activity. Data analysis using One Way ANOVA statistical test and descriptive. The result showed that the physical stability test, the three facial foam formulas have good physical stability and meet the pH requirements of topical cosmetic preparation. In the antibacterial activity test, it was found that the facial foam preparation of black cumin seed oil give inhibition of 15.37 mm (FI), 16.52 mm (FII) and 17.25 mm (FIII). Based on the one way ANOVA statistical data, the p value <0,05 which means that three is a significant difference in inhibition diameter between FI, FII and FIII which negative control and positive control. It is concluded that the facial foam preparations of black cumin seed oil was physically stable and based on antibacterial activity tests, it is known that FIII has the most bacterial resistance of 17.25 mm with medium resistance category.

show abstract

Section: Pendahuluanunclassified

Formulasi Dan Uji Aktivitas Antibakteri Facial Foam Minyak Biji Jintan Hitam (Nigella Sativa Oil)

Agistia,

Novita,

Nofriyanti

2023

jppie

View full text Add to dashboard Cite

show abstract

“…Penurunan kadar glukosa darah ini mengembalikan kondisi metabolisme normal sehingga dapat meningkatkan jumlah osteoblas secara signifikan seiring pertambahan dosis. Hal ini sejalan hasil penelitian yang memperlihatkan jumlah osteoblas pada hari ke-14 pada kelompok perlakuan pemberian minyak zaitun 0,7; 1,05; dan 1,4 ml/hari lebih tinggi dibandingkan pada kelompok kontrol dengan diabetes dan kelompok kontrol sehat (Santoso and Suryanto, 2017). Penurunan kadar glukosa darah pada pemberian minyak zaitun mengakibatkan peningkatan osteoblas yang tinggi, hal tersebut perlu menjadi perhatian sehingga diperlukan kebijaksanaan klinis dalam pemakaian minyak zaitun agar fungsi dari minyak zaitun dapat memberikan keuntungan pada bidang ortodonti.…”

Section: Pembahasanunclassified

Differences in Osteoblast Count and Its Effect on Orthodontic Movement of Diabetic Models’ Teeth After Oral Administration of Olive Oil

et al. 2022

View full text Add to dashboard Cite

Background: In patients with uncontrolled diabetes, an increase in Advanced glycation end products (AGEs) inhibits osteoblast differentiation so that the number of osteoblasts decreases and interferes with bone formation in orthodontic movement. Giving natural ingredients such as olive oil is proven to increase the number of osteoblasts. Purpose: To determine differences in the number of osteoblasts and their effect on the orthodontic movement of diabetic teeth after oral administration of olive oil. Method: 25 male guinea pigs divided into four groups: diabetic guinea pigs treated with olive oil at a dose of 0.7; 1.05; 1.4 ml/day, distilled water, and healthy guinea pigs were given aquadest. Alveolar bone tissue samples were taken on the 15th day after orthodontic application, and then the number of osteoblasts was calculated histologically. Result: In the diabetic model group treated with olive oil doses of 0.7; 1.05; 1.4 ml/day, distilled water, and healthy guinea pigs given aquades were 2.900 ± 0.678; 4.320 ± 0.497; 5.920 ± 0. 460; 0.200 ± 0.200; 1.320 ± 0.415. The study showed that the olive oil treatment group had more osteoblasts than the untreated group. Analysis one way ANOVA showed a very significant difference between the treatment group and the untreated group (p≤0.01), while the LSD test showed a significant difference between groups. The highest number of osteoblasts was found at a dose of 1.4 ml/day. Conclusion: There was an increase in osteoblasts in the orthodontic movement of diabetic teeth after oral administration of olive oil.

show abstract

“…Fructose intake for 12 weeks hold glycemic levels at 81 mg/dL (Tillman et al, 2014). Dextrose outperformed fructose after seven days of induction, while by 10%concentration raised glycemic at 148 mg/dL (Pramushinta et al, 2019) and by 40% at 154 mg/dL (Santoso & Suryanto, 2017).…”

Section: Introductionmentioning

confidence: 99%

The Weight Performance Stability of Mice on Modeling Obesity-Associated Hyperglycemia Induced by Dextrose Monohydrate

Putra

Santoso²,

Lutfiyati³

2022

BIOMEDNATPROCH

View full text Add to dashboard Cite

Previously, streptozotocin and alloxan were employed to imitate hyperglycemia in mice. High doses of sucrose were also induced as an alternative. Due to body mass index has been associated with hyperglycemia, the evidence of weight body index in various induction alternate kinds, however, have not been fully reported. Here-in, we report on the weight performance stability of mice body weight induced by dextrose, streptozotocin, and alloxan. To begin, all mice were divided into six groups of five, with one reserve in each. Following seven days of acclimatization, the mice were induced for nine days of hyperglycemia modeling; alloxan (Groups A and D), streptozotocin (Group B and E), dextrose monohydrate (Groups C and F). On preclinical research animals modelling related to obesity-associated hyperglycemia in mice, dextrose monohydrate induction was most successful than streptozocotin and alloxan induction, which performed best during the induction period (31% weight growth) and after metformin intervention (36% weight growth). Overall, dextrose monohydrate is most suitable to be used for modeling type 2 diabetes mellitus test animals rather than alloxan and streptozocotin.

show abstract

KOMPARASI EFEK PEMBERIAN MINYAK JINTAN HITAM (Nigella sativa) DENGAN MINYAK ZAITUN (Olea europea) TERHADAP PENURUNAN GLUKOSA DARAH PADA MENCIT (Mus musculus) STRAIN Balb/c

Cited by 4 publications

References 0 publications

Formulasi Dan Uji Aktivitas Antibakteri Facial Foam Minyak Biji Jintan Hitam (Nigella Sativa Oil)

Formulasi Dan Uji Aktivitas Antibakteri Facial Foam Minyak Biji Jintan Hitam (Nigella Sativa Oil)

Differences in Osteoblast Count and Its Effect on Orthodontic Movement of Diabetic Models’ Teeth After Oral Administration of Olive Oil

The Weight Performance Stability of Mice on Modeling Obesity-Associated Hyperglycemia Induced by Dextrose Monohydrate

Contact Info

Product

Resources

About