We discuss the manifestation of dynamical symmetries in quantum transport through nanostructures. The dynamical symmetry SO(4) manifested in the singlet-triplet excitations is shown to be responsible for several exotic effects in nano-devices: non-equilibrium Kondo effect in T-shape Double Quantum Dots, phonon-induced Kondo effect in transition-metal-organic complexes, Kondo shuttling in Nano-Electromechanical Single Electron Transistor. We consider the interplay between charge U (1) and spin SU (2) fluctuations in the vicinity of Stoner instability point and a non-monotonic behavior of a Tunneling Density of States in metallic quantum dots. The experiments showing important role of dynamical symmetries in nanostructures are briefly reviewed.