2021
DOI: 10.1055/a-1339-1635
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Konfokale Laser-Endomikroskopie des Kopf-Hals-Plattenepithelkarzinoms: eine systematische Übersicht

Abstract: Zusammenfassung Hintergrund Die konfokale Laser-Endomikroskopie (CLE) bietet mit einer bis zu 1000-fachen Vergrößerungsleistung die Möglichkeit, Interzellularräume in vivo zu erkennen. Die CLE hat sich in verschiedensten Fachbereichen bereits etabliert. Dieser Artikel gibt einen Überblick über die aktuelle Studienlage der CLE in der Diagnostik des Plattenepithelkarzinoms des Kopf-Hals-Bereichs. Material und Methoden Systematische Literaturrecherche in folgenden Online-Datenbanken: PubMed, M… Show more

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Cited by 7 publications
(1 citation statement)
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“…Concerning the 13 patients of this pilot trial, this resulted in a sensitivity, specificity, and accuracy for tumor detection or exclusion of 87.5, 80.0, and 84.6%, respectively. This is in the range reported for other CLE systems: According to data of other studies, the sensitivity and specificity of diagnosing head and neck squamous cell cancer is reported to 85.0-95.3% and 72.0-100%, respectively (19,20). Next step, a prospective trial with intraoperative in-vivo CLE classification compared to frozen section and final histopathology is needed.…”
Section: Discussionmentioning
confidence: 74%
“…Concerning the 13 patients of this pilot trial, this resulted in a sensitivity, specificity, and accuracy for tumor detection or exclusion of 87.5, 80.0, and 84.6%, respectively. This is in the range reported for other CLE systems: According to data of other studies, the sensitivity and specificity of diagnosing head and neck squamous cell cancer is reported to 85.0-95.3% and 72.0-100%, respectively (19,20). Next step, a prospective trial with intraoperative in-vivo CLE classification compared to frozen section and final histopathology is needed.…”
Section: Discussionmentioning
confidence: 74%