Benign perianal diseases are common pathologic lesions affecting millions worldwide which lead to significant morbidity and representing major medical and socioeconomic problems. This study aiming to evaluate the effect of life style modification's nursing program on post-operative outcomes of patients with selected benign perianal diseases. Subjects: A purposive sample of 100 adult patients undergoing a surgical procedure for hemorrhoid or/and anal fissure. Setting: The study was conducted at the general surgery department and general surgery out patient's clinics of Menoufia University hospital and Shebien El-kom Teaching hospital. Tools of the study: Four tools were utilized. Tool I: An interviewing questionnaire includes three parts: Personal data, medical data and patient's knowledge about diet and behavioral modification. Tool II: Post-operative complications assessment sheet. Tool III: Kegel exercise's performance checklist Tool IV: Self reported compliance assessment sheet. Results: There was statistically significant difference between study and control group regarding total means of knowledge, behavioral and exercises performance after intervention. There was statistically significant difference between study group and control group regarding post-operative complication. There were statistically significant differences regarding compliance about diet, behavioral modification and exercises in the study group than control group. Also, there was statistically significant reduction of recurrent manifestation of study group and control group after and six months. Conclusion: The implementation of lifestyle modifications program had led to improve healthy habits regarding diet, behavior and exercise practice that leading to reduce postoperative complication and also, is more effective on prevent the recurrence of manifestation after six months of follow up. Recommendations: Generalizing dietary and behavioral life style modifications among patients to prevent diseases initiation / symptoms aggravation reduce the incidence of surgery and disease recurrence after surgery.