The phenomenon of 1950s-1970s showed that material, financial, and technical assistance had been provided between developing countries. South-south cooperation (KSS) is one of the modalities of international development cooperation between developing countries to healp each other through mutual learning, sharing of experiences, and transfer of knowledge mechanisms in order to achieve mutual prosperity. The demand-driven pattern distinguishes SSC from other collaborations so that SSC considered as more prospective approach. There is no one-size-fits-all approach but it based on the needs of partner countries. By the time, SSC is no longer limites to the Asia-Africa context and as a progressive collaboration. By using descriptive qualitative methods and international regimes as an analytical framweork, the aim of this research is to show position that should be taken by SSC members in the middle of shifting of international order in which solidarity and acting collectively must be maintained. In the midst of various challenges such as the me-first policy, bilateral and regional approaches, new southern policy, and no single domination approach, SSC still has to maintain the principle of solidarity