stantly gathered, resulting in changes to vaccination policies, the purpose of this letter is to update SARS-CoV-2 vaccination information on patients with IBD.Currently, several studies are evaluating the effectiveness of SARS-CoV-2 vaccination in patients with IBD. A recent metaanalysis found that the pooled seroconversion rate after 2 doses of an mRNA vaccine in IBD patients was 95.17%, thus no lower than that in patients with other immune-mediated inflammatory diseases, including rheumatoid arthritis, systemic lupus erythematosus, and vasculitis. 4 The most recent data indicate that vaccinated IBD patients are well-protected against severe COVID-19 infection or death. 5,6 Thus, it is strongly recommended that unvaccinated IBD patients should be vaccinated as soon as possible.The evidence suggests that IBD patients receiving immunemodifying therapies may exhibit attenuated immune responses after vaccination, and protection against SARS-CoV-2 infection may wane over time. In a large-scale IBD cohort study performed in the UK (CLARITY-IBD), patients on infliximab evidenced 4-to 6-fold lower antibody levels than those of ve-