Korupensamine A, but not its atropisomer, korupensamine B, inhibits SARS-CoV-2 in vitro by targeting its main protease (Mpro)

NHC-Catalyzed Chemo- and Enantioselective Reaction between Aldehydes and Enals for Access to Axially Chiral Arylaldehydes

“…Axial chirals are significant in naturally occurring molecules, medicine, and materials . Axially chiral molecules have also been extensively explored as organic catalysts, ligands, and chiral auxiliaries in organic synthesis (Figure a).…”