Kounis syndrome: A rare case

Sunder, Ashok; Mohanty, Bijaya; Singh, Abha

doi:10.4103/jfmpc.jfmpc_355_20

Cited by 8 publications

(6 citation statements)

References 16 publications

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“…Ages 40 to 70 make up the majority of those affected (68%) [9]. In recent years, similar cases were reported by Sunder et al, Pirasath et al, and Thwe et al [5,10,11]. Kadeli et al reported a case of a severe allergic response to the angiography dye, which led to an inferior wall myocardial infarction [7].…”

Section: Discussionmentioning

confidence: 53%

Kounis Syndrome: Bee Sting-Induced Acute Myocardial Infarction

Borkar,

Hande,

Bankar

2023

Cureus

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Acute coronary syndrome or ST-elevation myocardial infarction that develops as a hypersensitive reaction following exposure to an allergen, such as chemicals or bee or wasp stings, is known as Kounis syndrome (KS). Based on angiographic characteristics, three kinds of KS have been identified. Multiple bee stings typically result in localized allergic reactions and anaphylaxis, but they can also occasionally induce severe systemic toxic reactions. Here, a case of KS in a 50-year-old male presented with swelling on the face and upper limbs and breathing difficulties resulting from bee stings which led to myocardial infarction. The risk of KS should be considered by the physician at the primary level in all situations involving multiple bee bites.

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Section: Discussionmentioning

confidence: 53%

Kounis Syndrome: Bee Sting-Induced Acute Myocardial Infarction

Borkar,

Hande,

Bankar

2023

Cureus

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“…21 The severity of serious systemic toxic reactions will generally depend on the amount of venom injected, which is correlated with the number of stings. Reported systemic toxic reactions from multiple bee stings are acute kidney injury, 22 acute myocardial infarction (KS), 23 cerebrovascular disease, 24 and death.…”

Section: Discussionmentioning

confidence: 99%

Angina and Arrhythmia Symptoms Following Multiple Bee Stings: Kounis Syndrome

Acehan¹,

Satar²,

Gülen³

et al. 2022

Wilderness & Environmental Medicine

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Kounis syndrome (KS) is an acute coronary syndrome including coronary spasm, acute myocardial infarction, and stent thrombosis preceded by an anaphylactic, anaphylactoid, allergic, or hypersensitivity injury. In this case presentation, we discussed Type I and Type II KS. Case 1 was a 72-y-old man who presented to the emergency department with allergic symptoms and chest pain that developed after multiple bee stings. Electrocardiography showed ST depression in the lateral leads. Case 2 was a 42-y-old woman who presented to the emergency department with complaints of chest pain, dizziness, and presyncope that developed after multiple bee stings. Mobitz Type II Block with right bundle branch block was observed in 42 beats•min -1 in the electrocardiography. Both patients were first treated for allergic reaction. Although early percutaneous coronary intervention was performed for graft thrombosis in Case 1, a permanent pacemaker was inserted in Case 2. The patients were discharged without any complications. Increasing physician awareness towards the existence of KS can prevent fatal outcomes with early diagnosis and treatment.

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“…In literature, the association of acute coronary syndrome/myocardial infarction with hymenopteran sting has been called Kounis Syndrome. [ 5 ] In a study of 152 patients of honeybee bite done by Laxmegowda et al ., bradycardia was reported in <0.7 percent patients. [ 7 ] Our case, though, had only transient bradycardia and did not require pacing.…”

Section: Discussionmentioning

confidence: 99%

“…Localized reactions include erythema, oedema, and pain whereas allergic reactions triggered by IgE, may cause urticaria, angioedema, bronchoconstriction, and anaphylactic shock. Systemic toxic reactions may cause acute kidney injury (AKI),[ 3 4 ] acute myocardial infarction (Kounis syndrome),[ 5 ] stroke,[ 6 ] peripheral neuropathy, glomerulonephritis, and even death. Mortality rates in various studies are as high as 15–25 percent.…”

Section: Introductionmentioning

confidence: 99%

Multi-organ dysfunction following honeybee bite—A rare entity

Prasad

Mehta

Satyanarayan

et al. 2020

J Family Med Prim Care

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Honeybee bites have been known to cause localized allergic reactions and anaphylaxis but systemic toxic reactions leading to multiorgan dysfunction is very rare. Serious complications like acute renal failure, acute myocardial infarction (Kounis syndrome) and even death have been reported as the complication of honeybee bite. Herein, we report a case of multiorgan dysfunction following honeybee bite, which was complicated with acute kidney injury, thrombocytopenia, bradycardia, keratitis, and deranged liver function along with localized allergic reaction and pain.

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Kounis syndrome: A rare case

Cited by 8 publications

References 16 publications

Kounis Syndrome: Bee Sting-Induced Acute Myocardial Infarction

Kounis Syndrome: Bee Sting-Induced Acute Myocardial Infarction

Angina and Arrhythmia Symptoms Following Multiple Bee Stings: Kounis Syndrome

Multi-organ dysfunction following honeybee bite—A rare entity

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