Kounis syndrome following multiple wasp stings: A case report

Basnet, Angela; Khadka, Manoj; Alismail, Abdullah; Shrestha, Dhan Bahadur; Thapa, Ashok

doi:10.1002/ccr3.7026

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…There are no reported deaths in the literature due to Kounis syndrome in the pediatric population. Sixteen out of the 330 case reports that we investigated of adult patients reported death due to Kounis syndrome or its complications [27,[93][94][95][96][97][98][99][100][101][102].…”

Section: Discussionmentioning

confidence: 99%

Exploring Variations in Etiology and Clinical Presentations of Kounis Syndrome Across Pediatric and Adult Populations: A Comprehensive Review

Youcefi,

Abu Saadeh,

Karaca

et al. 2024

Cureus

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Kounis syndrome (KS), recognized as a rare yet significant form of acute coronary syndrome precipitated by allergy-mediated mechanisms, poses diagnostic challenges due to its varied clinical presentations and under-recognition. Despite its relevance across diverse populations, comprehensive insights into age-specific characteristics and management remain limited. The analysis of 420 studies yielded a total of 466 case reports of Kounis syndrome, categorized into pediatric (n = 31) and adult (n = 435) populations. After rigorous screening, 330 adult and 20 pediatric case reports were included for further analysis. Triggering factors were identified, with drugs (other) being the most prevalent in both groups. The breakdown of triggering factors, such as drugs (antibiotics), bee/wasp stings, and contrast media, was elucidated. Variations in presenting symptoms, diagnostic investigations, and treatment modalities between pediatric and adult populations were observed. Notably, all pediatric cases were diagnosed with subtype I Kounis syndrome and demonstrated favorable outcomes without any reported fatalities, whereas adult cases exhibited a broader range of Kounis subtypes. Mortality was recorded solely in adult case reports, with no fatalities reported among pediatric cases. These findings underscore the importance of understanding the nuances in the clinical presentation and management of Kounis syndrome across different age groups.

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