Kwashiorkor in African Children in Durban

Anaemias of Marasmus and Kwashiorkor in Kenya

“…The results of these investigations show that the anaemias of marasmus and kwashiorkor are not usually severe (Scragg and Rubidge, 1960). They are predominantly hypochromic or normochromic with low mean corpuscular haemoglobin concentration in the former, although they have abundant haemosiderin in the form of massive aggregates in the marrow.…”

Serum Vitamin B12 and Folic Acid (P.G.A.) Levels in Hypoproteinaemia and Marasmus in Indian Children

“…The anaemia was hypochromic witb low mean corpuscular haemoglobin concentration in 12 patients (Gopalan and Ramalingaswami, 1955). In a study reported from Durban the anaemia was normocytic in 24, microcytic in four and macrocytic in four cases out of 36 children (Scragg and Rubidge, 1960). In a series of 21 cases of kwashiorkor in Africans, appreciable normocytic or macrocytic anaemia was found in six cases, while two-thirds of the children had haemoglobin levels of 9-0 g./l00 ml.…”

The Plasma Concentrations of Free and Protein-Bound Cortisol in Hypoproteinaemia

“…The easy laceration by mild trauma has been referred to as the ' ripped skin ' pheno¬ menon (Nugent, Warner, Dunn & Tyler, 1964). In kwashiorkor ulcération is fre¬ quently found in the flexures, on the buttocks or on the dorsum of the feet and minor traumata have been shown to play a part in localizing these skin lesions (Scragg & Rubidge, 1960). More than 75% of subjects with Cushing's syndrome have inter¬ mittent glucosuria and give a glucose tolerance curve of the diabetic type (Harrison et al 1962).…”

“…The obesity associated with Cushing's syndrome is thought to be due to the deposition of fat derived from gluconeogenesis under the influence of insulin (Harrison, Adams, Bennett, Resnik, Thorn & Wintrobe, 1962). The deposition of subcutaneous fat is also a feature of 'classical kwashiorkor' (Scragg & Rubidge, 1960). The major biochemical alterations in Cushing's syndrome are sodium retention, potassium loss, calcium loss, hyperglycaemia and glucosuria.…”