Kyphoplasty for occult and non-occult osteoporotic vertebral fractures: a retrospective study

Zhou, Zhangzhe; Sun, Zhiyong; Wang, Yimeng; Zhu, Xiaoyu; Zhou, Qian

doi:10.1177/0300060519894764

Cited by 3 publications

(4 citation statements)

References 22 publications

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“…Occult vertebral fractures (OVFs) are fractures with a small degree of trabecular disruption, where the intact cortical bone overlying the vertebral collapse makes it difficult to directly visualize on X-ray and computed tomography (CT) scans [ 1 ]. Based on the Genant semi-quantitative system, which classifies the degree of vertebral collapse into grades 0, 1, 2, 3, and 4, the change in OVF vertebrae is too small to be easily visualized, and is therefore graded = 0 [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, 79% of the OVFs observed could potentially collapse and develop into typical non-occult fractures within 3 months [ 7 ], which may lead to a variety of complications, such as peripheral soft tissue injury and spinal cord compression [ 7 ]. Therefore, it is necessary to identify potential OVFs for early disease management [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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The value of radiomics-based CT combined with machine learning in the diagnosis of occult vertebral fractures

Li,

Zeng,

et al. 2023

BMC Musculoskelet Disord

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Purpose To develop and evaluate the performance of radiomics-based computed tomography (CT) combined with machine learning algorithms in detecting occult vertebral fractures (OVFs). Materials and methods 128 vertebrae including 64 with OVF confirmed by magnetic resonance imaging and 64 corresponding control vertebrae from 57 patients who underwent chest/abdominal CT scans, were included. The CT radiomics features on mid-axial and mid-sagittal plane of each vertebra were extracted. The fractured and normal vertebrae were randomly divided into training set and validation set at a ratio of 8:2. Pearson correlation analyses and least absolute shrinkage and selection operator were used for selecting sagittal and axial features, respectively. Three machine-learning algorithms were used to construct the radiomics models based on the residual features. Receiver operating characteristic (ROC) analysis was used to verify the performance of model. Results For mid-axial CT imaging, 6 radiomics parameters were obtained and used for building the models. The logistic regression (LR) algorithm showed the best performance with area under the ROC curves (AUC) of training and validation sets of 0.682 and 0.775. For mid-sagittal CT imaging, 5 parameters were selected, and LR algorithms showed the best performance with AUC of training and validation sets of 0.832 and 0.882. The LR model based on sagittal CT yielded the best performance, with an accuracy of 0.846, sensitivity of 0.846, and specificity of 0.846. Conclusion Machine learning based on CT radiomics features allows for the detection of OVFs, especially the LR model based on the radiomics of sagittal imaging, which indicates it is promising to further combine with deep learning to achieve automatic recognition of OVFs to reduce the associated secondary injury.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The value of radiomics-based CT combined with machine learning in the diagnosis of occult vertebral fractures

Li,

Zeng,

et al. 2023

BMC Musculoskelet Disord

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“…The conservative treatments need prolonged bed rest and drug therapy [4]. If patients are associated with a delay in accepting formal conservative treatment, multiple complications secondary to OVCF will occur, such as back pain, kyphotic deformity, a reduction of life quality, increased magnitude of vertebral compression, deep vein thrombosis, and pulmonary infection [5,6].…”

Section: Introductionmentioning

confidence: 99%

Percutaneous vertebral-disc plasty for thoracolumbar very severe osteoporotic vertebral compression fractures

Jiang

Zhang

Bao

et al. 2022

Preprint

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Background: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental instability, and kyphosis due to thoracolumbar very severe osteoporotic vertebral compression fractures (vsOVCFs).Methods: 31 patients with thoracolumbar vsOVCFs were retrospectively reviewed. All the patients were divided into the PVP group and the PVDP group. The visual analogue scale (VAS), Oswestry Disability Index (ODI), local kyphosis angle, and disc height were recorded preoperatively and postoperatively.Results: Significant postoperative improvements on the VAS, ODI, and the local kyphosis angle (LKA) were shown, compared with the preoperative values in both groups (p < 0.05). The average VAS, ODI, and LKA for patients in the PVP group were increased compared to those in the PVDP group were observed at the last follow-up (p < 0.05). The DHA, DHP, and LKA were seen to be maintained in the PVDP group at the last follow-up (p > 0.05). In those parameters, the change was significantly lower in the PVDP group at the last follow-up. (p <0.05).Conclusions: PVDP may be a feasible and effective technique for the treatment of very severe OVCFs, that can restore intervertebral height, provide segmental stabilizing and improve kyphosis in the short term.

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“…The conservative treatments need prolonged bed rest and drug therapy ( 4 ). If patients are associated with a delay in accepting formal conservative treatment, multiple complications secondary to OVCF will occur, such as back pain, kyphotic deformity, a reduction of life quality, increased magnitude of vertebral compression, deep vein thrombosis, and pulmonary infection ( 5 , 6 ).…”

Section: Introductionmentioning

confidence: 99%

Percutaneous vertebral-disc plasty for thoracolumbar very severe osteoporotic vertebral compression fractures: A randomized controlled study

Jiang

Zhang²,

Bao³

et al. 2022

Front. Surg.

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PurposeTo compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental instability, and kyphosis due to thoracolumbar very severe osteoporotic vertebral compression fractures (vsOVCFs).MethodsThis prospective randomized controlled study included elderly patients with thoracolumbar vsOVCFs. All the patients were randomly allocated into the PVP group (who underwent conventional PVP) and the PVDP group (who underwent PVP combined percutaneous cement discoplasty). The visual analogue scale (VAS), Oswestry Disability Index (ODI), local kyphosis angle, and disc height were recorded preoperatively and postoperatively.ResultsSignificant postoperative improvements in the VAS, ODI, and the local kyphosis angle (LKA) were shown, compared with the preoperative values in both groups (p < 0.05). The average VAS, ODI, and LKA for patients in the PVP group were increased compared to those in the PVDP group observed at the last follow-up (p < 0.05). The DHA, DHP, and LKA were seen to be maintained in the PVDP group at the last follow-up (p > 0.05). The change was significantly lower in the PVDP group at the last follow-up in those parameters (p < 0.05).ConclusionPVDP may be a feasible and effective technique for the treatment of very severe OVCFs, that can restore intervertebral height, provide segmental stabilizing and relieve back pain in the short term.

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Kyphoplasty for occult and non-occult osteoporotic vertebral fractures: a retrospective study

Cited by 3 publications

References 22 publications

The value of radiomics-based CT combined with machine learning in the diagnosis of occult vertebral fractures

The value of radiomics-based CT combined with machine learning in the diagnosis of occult vertebral fractures

Percutaneous vertebral-disc plasty for thoracolumbar very severe osteoporotic vertebral compression fractures

Percutaneous vertebral-disc plasty for thoracolumbar very severe osteoporotic vertebral compression fractures: A randomized controlled study

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