Kyrieleis plaques in herpes zoster virus-associated acute retinal necrosis: a case report

Empeslidis, Theodoros; Konidaris, Vasileios; Brent, A; Vardarinos, Athanasios; Deane, James

doi:10.1038/eye.2013.110

Cited by 18 publications

(13 citation statements)

References 6 publications

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“…Griffin and Bodian2 later used the term segmental retinal periarteritis to describe these changes, which appear as focal or segmental yellowish-white accumulations around retinal arteries, typically near or adjacent to an area of active retinal infection or inflammation. While Kyrieleis plaques are observed most often in eyes with active Toxoplasma gondii retinochoroiditis,3 they have also been reported with Rickettsia conorii , Mycobacterium tuberculosis , Treponema pallidum ,4 and varicella-zoster virus (VZV) and cytomegalovirus (CMV) infections 5 6…”

Section: Introductionmentioning

confidence: 99%

New appraisals of Kyrieleis plaques: a multimodal imaging study

et al. 2016

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Section: Introductionmentioning

confidence: 99%

New appraisals of Kyrieleis plaques: a multimodal imaging study

et al. 2016

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“…Kyrieleis’ arteriolitis have been only rarely reported in patients with ARN. 1 Kyrieleis’ plaques have been postulated to be due to calcific deposits in the arterial walls or migration of exudates from active choroiditis to the periarterial sheaths, with compartmentalisation of the exudates due to anatomical variations. 1 ARN should be considered as a differential diagnosis when Kyrieleis’ plaques are observed.…”

Section: Discussionmentioning

confidence: 99%

“…Multiple areas of white retinal swelling in the posterior pole with macula involvement were apparent ( figure 1 ) in the right eye. Obliterated arterioles with perivascular sheathing (Kyrieleis’ plaques) 1 were detected ( figures 1 and 2 ). Ultrasound showed bilateral RDs.…”

Section: Case Presentationmentioning

confidence: 98%

Sequential retinal necrosis secondary to varicella zoster in unrecognised long-standing HIV infection: patient safety report

et al. 2018

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A retired woman with left ophthalmic shingles of over 2 years’ duration attended with bilateral vision loss and systemic upset. Acute retinal necrosis with detachment was detected on right fundus examination. Cataract in left eye precluded funduscopy. Ocular ultrasonography revealed fibrotic retinal detachment in the left eye. MRI brain and orbits also showed signals of retinal detachment. No abnormal MRI signal within the optic nerve or brain was found. Varicella zoster virus was detected in ocular aqueous and blood samples. High-dose intravenous acyclovir was administered. HIV test was positive with a very low CD4 count. Antiretroviral medications were prescribed. There was no recovery of vision. She was certified as blind, and social services were involved in seeking to provide alterations to her home in view of her severe disability. This case highlights the importance of suspecting HIV in patients with severe or chronic ophthalmic shingles. Images and implications for clinical practice are presented.

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“…Se cree que se debió a una respuesta inmune, al depósito en la pared de las arterias de células inflamatorias y detritus; mientras que otros lo debaten, porque las placas pueden persistir a pesar de la resolución de la infección y del tratamiento con esteroides. No empeoran el pronóstico de la enfermedad 8,9 . El rápido inicio del tratamiento, la presencia de un área de necrosis limitada en ambos ojos, con poco componente arterítico oclusivo y la ausencia de complicaciones han hecho que nuestro paciente tenga evolución favorable de su NRA.…”

Section: Discussionunclassified