L'albinisme oculocutané: mises au point clinique, historique et anthropologique

Jeambrun, Pascale

doi:10.1016/s0929-693x(98)80136-x

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…Albinism has long been recognized, an early account being provided by Pliny in the first century AD (quoted in Witkop et al [87]). Individuals with albinism are visually obvious and exceptional and as such have been the object of mythology, bigotry and cruel exploitation [88][89][90][91]. The term albinism (Latin, albawhite) refers to a group of inheritable disorders of melanin pigmentation but with normal numbers and disposition of melanocytes in skin (and eyes and hair) [87,88,92].…”

Section: Skin Cancer In Albinosmentioning

confidence: 99%

Was skin cancer a selective force for black pigmentation in early hominin evolution?

Greaves

2014

Proc. R. Soc. B.

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Melanin provides a crucial filter for solar UV radiation and its genetically determined variation influences both skin pigmentation and risk of cancer. Genetic evidence suggests that the acquisition of a highly stable melanocortin 1 receptor allele promoting black pigmentation arose around the time of savannah colonization by hominins at some 1-2 Ma. The adaptive significance of dark skin is generally believed to be protection from UV damage but the pathologies that might have had a deleterious impact on survival and/or reproductive fitness, though much debated, are uncertain. Here, I suggest that data on age-associated cancer incidence and lethality in albinos living at low latitudes in both Africa and Central America support the contention that skin cancer could have provided a potent selective force for the emergence of black skin in early hominins.

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Section: Skin Cancer In Albinosmentioning

confidence: 99%

Was skin cancer a selective force for black pigmentation in early hominin evolution?

Greaves

2014

Proc. R. Soc. B.

View full text Add to dashboard Cite

show abstract

L'albinisme oculocutané: mises au point clinique, historique et anthropologique

Cited by 1 publication

References 24 publications

Was skin cancer a selective force for black pigmentation in early hominin evolution?

Was skin cancer a selective force for black pigmentation in early hominin evolution?

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