l-Arginine modified multi-walled carbon nanotube/sulfonated poly(ether ether ketone) nanocomposite films for biomedical applications

Kaya, Hatice; Bulut, Osman; Kamali, Ali Reza; Ege, Duygu

doi:10.1016/j.apsusc.2018.03.046

Cited by 34 publications

(6 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because the amide, imide and guanidine functional groups on the L-arginine molecule have a significant antibacterial effect after halogenation, in this work, L-arginine was chosen as the precursor of N-haloamine antibacterial molecules. L-arginine coating is able to maintain the original physical and mechanical properties of cotton fabric to the greatest extent, and has good biocompatibility [16], hence it does not cause irritation when it is in contact with human skin.…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: Contact/Release Coordinated Antibacterial Cotton Fabrics Coated with N-Halamine and Cationic Antibacterial Agent for Durable Bacteria-Killing Application

Han

Liu

Zhu

et al. 2020

IJMS

View full text Add to dashboard Cite

Coating a cationic antibacterial layer on the surface of cotton fabric is an effective strategy to provide it with excellent antibacterial properties and to protect humans from bacterial cross-infection. However, washing with anionic detergent will inactivate the cationic antibacterial coating. Although this problem can be solved by increasing the amount of cationic antibacterial coating, excessive cationic antibacterial coating reduces the drapability of cotton fabric and affects the comfort of wearing it. In this study, a coordinated antibacterial coating strategy based on quaternary ammonium salt and a halogenated amine compound was designed. The results show that the antibacterial effect of the modified cotton fabric was significantly improved. In addition, after mechanically washing the fabric 50 times in the presence of anionic detergent, the antibacterial effect against Staphylococcus aureus and Escherichia coli was still more than 95%. Furthermore, the softness of the obtained cotton fabric showed little change compared with the untreated cotton fabric. This easy-to-implement and cost-effective approach, combined with the cationic contact and the release effect of antibacterial agents, can endow cotton textiles with durable antibacterial properties and excellent wearability.

show abstract

Section: Introductionmentioning

confidence: 99%

RETRACTED: Contact/Release Coordinated Antibacterial Cotton Fabrics Coated with N-Halamine and Cationic Antibacterial Agent for Durable Bacteria-Killing Application

Han

Liu

Zhu

et al. 2020

IJMS

View full text Add to dashboard Cite

show abstract

“…Polyetheretherketone (PEEK) has great potential in the application of orthopaedic implants because of its nontoxicity, nonsensitization, wear resistance, easy processing and forming, and similar mechanical properties to the skeleton. − Therefore, in the late 1990s, it was officially approved as an implantable biomaterial by the FDA …”

Section: Introductionmentioning

confidence: 99%

Mixed Modification of the Surface Microstructure and Chemical State of Polyetheretherketone to Improve Its Antimicrobial Activity, Hydrophilicity, Cell Adhesion, and Bone Integration

Ding

Chen

et al. 2019

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

Polyetheretherketone (PEEK) is becoming an attractive surgical implant material in the biomedical field. However, its hydrophobicity and biological inertia have seriously hindered its development in the field of biomaterials and application in clinic. In this work, a mixed modification approach of the surface structure and chemical state was proposed to improve hydrophilicity and bioactivity of PEEK and meanwhile endowed it with antimicrobial properties. First, the effect of mixed acids of nitric acid and concentrated sulfuric acid with different volume ratios on the surface morphology of PEEK was quantitatively investigated, so as to obtain an optimal mixed acid of nitric acid and concentrated sulfuric acid with a volume ratio that could create a multilevel porous structure. Based on this, chemical grafting of ethylenediamine was conducted to achieve amination on the surface of the PEEK. The results showed that such double modification of the surface structure and chemical state could endow PEEK not only with antimicrobial activity but also with good hydrophilicity, cell compatibility, and bioactivity, which were beneficial to improve the bone integration ability of PEEK greatly.

show abstract

“…Here, the resazurin molecule is used as an indicator of cell viability and proliferation through the reduction of resazurin by mitochondrial metabolic activity in living cells [45,46]. Briefly, the old medium on the scaffold-cell construct was refreshed with new culture medium including 10% Alamar Blue and then cellseeded scaffolds were incubated for 4 h. At the end of incubation time, 100 µl of solution from each well was transferred into 96 well-plates.…”

Section: Cell Proliferation and Morphologymentioning

confidence: 99%

CNT incorporation improves the resolution and stability of porous 3D printed PLGA/HA/CNT scaffolds for bone regeneration

Kaya,

Arıcı,

Bulut

et al. 2023

Biomed. Mater.

Self Cite

View full text Add to dashboard Cite

In this study, 3D printed porous poly(lactide-co-glycolide) (PLGA) and its nanocomposites with 5 wt. % hydroxyapatite (HA) and 0.5, 1 and 2 wt. % multi-walled carbon nanotubes (MWCNT) scaffolds were fabricated by using extrusion-based printing. The printing parameters were optimized by rheological studies. The rheological studies demonstrated shear thinning properties for all compositions and an increase in storage modulus was observed after the addition of MWCNT. Porous PLGA/HA/MWCNT scaffolds were printed by applying a pressure of 4.76 bar at 125 ⁰C. The addition of 0.5 wt. % of MWCNT reduced the strut size and increased the porosity from 42% to 60%. The increase of storage modulus and decrease of strut size was related to hydrogen bonding between MWCNT, HA and PLGA which ultimately improved shape fidelity. The scaffolds were characterized by analysis of their chemical structure, water contact angle measurement, in vitro bioactivity test, biodegradation test, mechanical analysis, and in vitro cell studies. The scaffolds were found to be more hydrophilic by the incorporation of MWCNTs. Also, degradation studies showed that the microstructure of the scaffold became more stable with the addition of HA and MWCNT. The compressive modulus of PLGA/HA/CNT2 scaffold was found to be 548.5 MPa which is found suitable to replace cancellous bone. The scaffolds were found highly biocompatible which is possibly due to alignment of MWCNT and PLGA during 3D printing process. Alizarin red staining indicated improvement of mineralization of MC3T3-E1 cells on the MWCNT incorporated porous 3D scaffolds. The results suggest that the produced porous 3D printed PLGA/HA/MWCNT scaffolds are promising for bone regeneration applications.

show abstract

l-Arginine modified multi-walled carbon nanotube/sulfonated poly(ether ether ketone) nanocomposite films for biomedical applications

Cited by 34 publications

References 52 publications

RETRACTED: Contact/Release Coordinated Antibacterial Cotton Fabrics Coated with N-Halamine and Cationic Antibacterial Agent for Durable Bacteria-Killing Application

RETRACTED: Contact/Release Coordinated Antibacterial Cotton Fabrics Coated with N-Halamine and Cationic Antibacterial Agent for Durable Bacteria-Killing Application

Mixed Modification of the Surface Microstructure and Chemical State of Polyetheretherketone to Improve Its Antimicrobial Activity, Hydrophilicity, Cell Adhesion, and Bone Integration

CNT incorporation improves the resolution and stability of porous 3D printed PLGA/HA/CNT scaffolds for bone regeneration

Contact Info

Product

Resources

About