“…46,47,51,57 Methodological quality issues are reported in Table 2. Out of fifteen studies, five did not analyze data with sufficient coverage of the identified sample, 46,47,50,51,55 four did not use reliable diagnostic criteria for knee OA 47,51,52,57 (i.e. self-reported diagnosis), eight did not present reliability of the method used to identify knee OA, 46,47,49,51,52,54,56,57 twelve did not report subpopulations using objective criteria 44---46,48---54,57,58 and eleven did not reach appropriate sample size.…”