L’atteinte hépatique au cours du syndrome auto-immun multiple : à propos de 15 cas

Màamouri, N.; Kchir, H.; Mebazza, A.; Naçef, I. Ben; Belkahla, N.; Ouerghi, H.; Hariz, F. Ben; Chouaïb, S.; Chaabouni, H.; Osman, A. Ben; Mami, N. Ben

doi:10.1016/j.revmed.2010.03.278

Cited by 1 publication

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“…MAS were an entity rarely described in the African literature. In North Africa [14]- [20], as in Africa South of the Sahara [12] [13], the entity is reported as an isolated observation or in short series Open Journal of Rheumatology and Autoimmune Diseases was likely to be underestimated in sub-Saharan Africa, as there is a considerable increase in the incidence of autoimmune diseases in those regions [21] [22] [23] [24]. This entity should be considered, because there is evidence that 25 to 30 percent of autoimmune disease are thought to progress to polyautoimmunity [2].…”

Section: Discussionmentioning

confidence: 99%

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Multiple Autoimmune Syndrome: A Study of 25 Senegalese Cases

Niasse¹,

Kane²,

Mabom³

et al. 2020

OJRA

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Introduction: Multiple autoimmune syndrome is rarely described in the African literature. We report 25 cases. Patients and Method: A Retrospective, descriptive study was carried out in the Rheumatology Department of Aristide Le Dantec University Hospital in Dakar from 2013 to September 2019. Patients with at least 3 distinct autoimmune diseases were included. Results: Twenty-five cases of multiple autoimmune syndrome were collected in 23 women and 2 men, with a mean age of 42.4 years (extremes: 24 and 67 years). The mode of discovery of the disease was a connective tissue disease in 19 cases (76%) and an organ-specific autoimmune disease in 6 cases. According to Humbert and Dupond's classification, 18 patients (72%) had both type 2 and type 3 criteria. An isolated type 2 was noted in 5 cases (20%) and an isolated type 3 in 1 case (4%). One case (4%) was unclassifiable. The evolution under treatment was marked by remission in 84% of cases. Conclusion: Multiple autoimmune syndromes account for 5.66% of the autoimmune diseases in our study. They predominate in young women with a mean age of 42.4 years. Not all entities were classifiable by the Humbert and Dupond's classification. The evolution under treatment was marked by remission in 84% of cases.

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Section: Discussionmentioning

confidence: 99%

“…The presence of 5 autoimmune diseases in a MAS is an exceptional situation [14] [29] [30] [32] [43]. MAS fitted both Humbert and Dupont types 2 and 3 in 18 cases (72%), type 2 in 5 cases (20%) and type 3 in 1 case (4%).…”

Section: Discussionmentioning

confidence: 99%