L'azione protettiva dell'acido tioctico nell'intossicazione da cianuro di potassio

Cutolo, E; Reduzzi, F

doi:10.1007/bf02170519

Cited by 4 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During the 1950s, experimental studies showed that lipoic acid; a naturally occurring substance can prevent the development of alloxan diabetes in rats [1]. The use of oral lipoic acid in diabetic neuropathy has been reported as early as the 1960s [2].…”

mentioning

confidence: 99%

The use of alpha-lipoic acid supplementation in diabetes: The available evidence

Al-Mosawi¹

2022

CTBR

View full text Add to dashboard Cite

Dietary health supplements have been increasingly used in the treatment and prevention of chronic disorders. During the previous years, lipoic acid has been reported to have a beneficial effect on diabetes and some of its complications. The aim of this paper is to review the evidence provided by lipoic acid research findings relevant to its use in diabetes. Since, the1950s, there has been accumulating experimental evidence showing that that lipoic acid, a naturally occurring substance, has a protective effect against the development of diabetes and its complications especially neuropathy. The beneficial use of oral lipoic acid in diabetic neuropathy has been reported mostly from Germany as early as the 1960s. Conclusion: There is convincing research evidence suggesting that lipoic acid has a benerficial effects in diabetes, and is particularly useful in the prevention and treatment of diabetic neuropathy. The beneficial effects of lipoic acid in diabetes and diabetic neuropathy are attributed to increasing insulin sensitivity, reduction of hyperglycemia-induced oxidative stress, and lipid peroxidation. Lipoic acid can possibly help in preventing diabetes in susceptible individuals, and the current expert opinion suggests that lipoic acid can be used in patients with patients with impaired glucose tolerance.

show abstract

mentioning

confidence: 99%