L-PRF Associated With Bio-Oss® As an Optional Treatment for Radicular Cyst: Case Report

Abstract

In order to regenerate bone and soft tissue, multiples types of treatment were developed including the use of bone grafting, membranes and growth factor/cytokines/host modulating agent. Leukocyte-platelet-rich fibrin (L-PRF) is a second-generation platelet concentrate that forms a natural fibrin matrix with immune regulation node and inflammation retrocontrol proprieties, which can be useful in healing of apical defects. In the present case, bovine bone substitute graft was associated with L-PRF clot to achieve bone and soft tissue regeneration in a periapical inflammatory lesion. The case developed with a satisfactory bone healing, which suggests that the association of L-PRF and bone grafts may affect positively in the regeneration of bone in wide circumferential apical defects.