L’utilizzo di cellule staminali in ortopedia pediatrica

Memeo, Antonio; Pedretti, Leopoldo; Rossi, Laura Lucia; Calabrò, F; Albisetti, W.

doi:10.1007/s10261-012-0032-z

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Cited by 2 publications

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“…Other centres prefer to delay lengthening until early adolescence to increase the patient's participation with rehabilitation [20]. New procedures based on the use of autologous bone growth stimulators, such as mesenchymal stem cells or growth factors, are now being studied to improve primary bone healing and to treat complications [21,22].…”

Section: Discussionmentioning

confidence: 98%

Autologous fat graft as treatment of post short stature surgical correction scars

Maione¹,

Memeo

Pedretti

et al. 2014

Injury

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Section: Discussionmentioning

confidence: 98%

Autologous fat graft as treatment of post short stature surgical correction scars

Maione¹,

Memeo

Pedretti

et al. 2014

Injury

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Mesenchymal stem cells as adjuvant therapy for limb lengthening in achondroplasia

Memeo¹,

Verdoni

Ingraffia³

et al. 2019

Journal of Pediatric Orthopaedics B

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Staged leg lengthening allows achondroplastic dwarfs to reach nearly normal height, but it takes long periods of external fixation and it can be burdened by delayed unions. Between 2009 and 2013, eight achondroplastic dwarfs showed delayed unions in the callus formation during femoral lengthening stages in our institute. We performed in-situ injections of bone marrow-derived stem cell concentrates. Patients underwent monthly clinical and radiographic assessment for determination of the healing rate. All eight patients showed an improvement in the regenerated bone, with an average healing index of 23.1 days/cm (range: 18.7–23.8 days/cm). The complete recovery of the delayed consolidation took on an average of 5.2 months (range: 2–10 months). The use of cellular therapy in these patients could represent an innovative application.

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L’utilizzo di cellule staminali in ortopedia pediatrica

Cited by 2 publications

References 21 publications

Autologous fat graft as treatment of post short stature surgical correction scars

Autologous fat graft as treatment of post short stature surgical correction scars

Mesenchymal stem cells as adjuvant therapy for limb lengthening in achondroplasia

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