L-wave in severe mitral stenosis

Bhasin, Dinkar; Arora, Gaurav Kumar; Gupta, Anunay; Isser, H.S.

doi:10.1080/00015385.2021.1886407

Cited by 1 publication

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“… 37 , 41 In humans, L waves become evident in pathologic conditions characterized by decreased LV diastolic active relaxation, increased LV stiffness, increased filling pressures or some combination of these, such as LV hypertrophy, 38 , 43 , 44 severe mitral valve disease, 45 heart diseases characterized by severe LV systolic dysfunction, 22 , 43 and AF. 20 , 36 , 45 In these patients, detection of L waves has been associated with increased LA pressure, pseudonormal filling state, and higher probability of future hospitalization for heart failure and cardiac death. 20 , 21 , 38 , 43 , 44 In our study, L waves were identified in 60% of dogs with AF.…”

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confidence: 99%

Prevalence and prognostic role of L wave and selected clinical and echocardiographic variables in dogs with atrial fibrillation

Romito

Darida

Valente

et al. 2022

Veterinary Internal Medicne

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Background: Information regarding the frequency of L waves and their prognostic relevance in dogs with secondary atrial fibrillation (AF) is limited.Hypothesis/Objectives: To determine whether L waves occur and ascertain their prognostic role, as well as the role of other clinical and echocardiographic variables in dogs with AF.Animals: Fifty-five dogs with AF associated with myxomatous mitral valve disease or dilated cardiomyopathy.Methods: Retrospective, multicenter observational study. In addition to L waves analysis, other clinical and echocardiographic variables, including type of antiarrhythmic treatment, were evaluated. A survival analysis was performed to test for predictors of cardiac death and all-cause mortality using Cox proportional hazards regression models.Results: L waves were evident in 33/55 dogs (60%, 95% confidence interval[CI] = 47%-72%) but their presence did not influence outcome. Increased left ventricular end-systolic diameter normalized for body weight (LVSDn) was a significant predictor of both cardiac death (hazard ratio [HR] = 4.41, 95%

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