L3 and adult Ostertagia (Teladorsagia) circumcincta exhibit cyanide sensitive oxygen uptake

Letter to the Editor: Two of the significant omissions from a “general” model of respiratory energy transduction

“…Of these, two omissions are of particular significance: the alternative oxidase (AOX) and the "external" NAD(P)H dehydrogenase (NDH ext ). Both of these enzymes are found in the mitochondria of most plant species, but AOX is also (or can be) present in the mitochondria of many fungi, nematodes, and a variety of other nonmammalian organisms (1,4,5).…”

“…Our experience with plant, fungal, nematode, and mammalian mitochondrial and various bacterial electron transfer chains persuades us that differences between them tend to be physiologically significant (1,4,5). For example, both AOX and the NDH ext [as well as a homologue of the mammalian uncoupling protein also omitted from the model ( 6)] have been implicated (2,3) in the high rates of relatively uncontrolled electron transfer that increase plant tissue temperature enough to melt surrounding snow.…”