La conciliation des traitements médicamenteux : logigramme d’une démarche efficiente pour prévenir ou intercepter les erreurs médicamenteuses à l’admission du patient hospitalisé

Doerper, S.; Morice, S.; Piney, D.; Dony, A.; Baum, Thomas; Perrin, F.; Guillaume, V.; Vidal, A.; Ferry, Olivier; Peter, N.; Azizi, Yassine; Vouaux, V.; Rosa, D.; Dufay, E.

doi:10.1016/j.phclin.2013.03.006

Cited by 18 publications

(11 citation statements)

References 7 publications

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“…Because the process of establishing the medication list was not sufficiently formalised or organised by any of these health professionals, it was repeated in at least two healthcare units: the emergency department and the first hospitalisation care unit. In a previous study, we noted that only 24.1% of medication prescriptions written up in the emergency department were complete, and 81.3% in follow-up wards 11. According to the study of Caglar et al ,29 only 13% of medication prescriptions were complete, and in the study of Barillet et al 9 the proportion was 25%.…”

Section: Discussionmentioning

confidence: 86%

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The clinical impact of medication reconciliation on admission to a French hospital: a prospective observational study

et al. 2015

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ObjectiveThis study was designed to assess the clinical impact of medication reconciliation using two criteria: the number of inpatients who had experienced at least one medication error; the severity of the potential harm associated with these detected errors.MethodThe study was a prospective observational one. The eligible population included patients aged 65 and over subjected to medication reconciliation at admission. The potential severity of medication errors was evaluated independently by the physician in charge of the patient and by the pharmacist involved in the medication reconciliation process. Severity assessment took account of the drug(s) involved in the error, the type of medication error, and the patient's clinical and biological data.ResultsFrom January 2011 to September 2012, 1799 medication errors were recorded among the 1670 patients subjected to medication reconciliation who were hospitalised from the emergency department. At least one medication error occurred for 744 (44.6%) of these patients. There were 87 medication errors associated with potentially major severity (5.6%). These concerned 67 patients (4.2%). The most prevalent error was omission. Cardiovascular and anticoagulant drugs were the drugs most frequently involved in these serious medication errors. Arrhythmia, haemorrhage, thrombosis, hyperglycaemia and hypoglycaemia were identified as the most likely harms that could have occurred.ConclusionsThe detection of cases of serious potential harm shows the clinical impact of medication reconciliation. It would be interesting to perform a multicentred assessment using indicators such as the number of inpatients experiencing at least one serious medication error. This could help to promote medication reconciliation as essential for patient safety.

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Section: Discussionmentioning

confidence: 86%

“…The medication reconciliation process has been implemented since 2009 in Lunéville Hospital, and its performance has been described in a recent publication 11. It involves patients aged 65 years and over admitted through the emergency department.…”

Section: Methodsmentioning

confidence: 99%

The clinical impact of medication reconciliation on admission to a French hospital: a prospective observational study

et al. 2015

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“…Dans un contexte de risque spécifique lié à l'organisation des parcours de soins, à l'origine d'incohérence potentielle entre les traitements, de points de rupture dans la continuité des traitements, la nécessité de mettre en place une conciliation médicamenteuse à l'entrée et à la sortie de l'hôpital, portant particulièrement sur les produits à risque, est capitale [18][19][20][21].…”

Section: Problèmes De Rupture Dans La Chaîne Des Soinsunclassified

Interventions des pharmaciens sur les prescriptions ambulatoires dans le cadre de l’activité de rétrocession d’un centre hospitalier universitaire

Chappuy

Garcia²,

Uhres

et al. 2015

Annales Pharmaceutiques Françaises

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These results show the importance of the analysis of outpatient prescriptions before dispensing and the need to have all prescriptions, clinical and biological elements and to develop interprofessionality. The implementation of a platform for dematerialized data exchanges between professionals, including data from the pharmaceutical patient record should contribute to improving drug management of the patient.

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“…Furthermore, the French ENEIS 2 study showed that 1.3% of hospital stays originated from serious ADE in 2009 [ 2 ]. Data from the literature show that older patients and children are at high risk of medication errors specifically at hospital admission and discharge [ 3 – 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…In accordance with the World Health Organization (WHO) ("Assuring medication accuracy at transitions in care”) and French health authorities [ 6 ], developing programs on the securing patients’ medications is crucial through the course of care [ 7 ]. Indeed, transitions between community and hospital settings are at the highest risk of medication errors [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of a pharmacist-led medication review on hospital readmission in a pediatric and elderly population: study protocol for a randomized open-label controlled trial

Renaudin

Baumstarck

Daumas

et al. 2017

Trials

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BackgroundEarly hospital readmission of patients after discharge is a public health problem. One major cause of hospital readmission is dysfunctions in integrated pathways between community and hospital care that can cause adverse drug events. Furthermore, the French ENEIS 2 study showed that 1.3% of hospital stays originated from serious adverse drug events in 2009. Pharmacy-led medication reviews at hospital transitions are an effective means of decreasing medication discrepancies when conducted at admission or discharge. However, it is difficult to assess the true impact of pharmacist-led medication reviews in specific high-risk populations, such as pediatric and geriatric populations.In such a context, it is important to demonstrate the effectiveness of medication reconciliation as part of a standardized medication review process—in pediatric and elderly populations—on all-cause readmissions in a large randomized controlled clinical trial.The aim of this study is to assess the impact of the pharmacist-led medication review on the rate of readmissions and/or death after hospital discharge and patient treatment satisfaction.Methods/designThe study is a randomized controlled clinical trial. A total of 1400 hospitalized patients will be randomized in two groups: (1) the experimental group (group receiving a pharmacist-led medication review) and (2) the control group (group receiving usual care). The pharmacist-led medication review process includes medication reconciliation, treatment review and medication liaison service. The primary endpoint will be the rate of readmissions and/or death at 30 days following initial hospitalization discharge. The secondary endpoints will be the rate of hospital readmission, the rate of emergency department visits, the rate of mortality, the number of consultations and patient treatment satisfaction at 30 days following initial hospitalization discharge.DiscussionA randomized controlled trial provides the most extensive evidence on the impact of pharmacist-led medication reviews on early hospital readmission for extreme age populations.Trial registrationCurrent Controlled Trials, NCT02734017. Registered on 4 May 2016.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-017-1798-6) contains supplementary material, which is available to authorized users.

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La conciliation des traitements médicamenteux : logigramme d’une démarche efficiente pour prévenir ou intercepter les erreurs médicamenteuses à l’admission du patient hospitalisé

Cited by 18 publications

References 7 publications

The clinical impact of medication reconciliation on admission to a French hospital: a prospective observational study

The clinical impact of medication reconciliation on admission to a French hospital: a prospective observational study

Interventions des pharmaciens sur les prescriptions ambulatoires dans le cadre de l’activité de rétrocession d’un centre hospitalier universitaire

Impact of a pharmacist-led medication review on hospital readmission in a pediatric and elderly population: study protocol for a randomized open-label controlled trial

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