La cytologie exfoliatrice œsophagienne à I’aveugle par capsule abrasive dans la surveillance des patients à haut risque de cancer œsophagien

Costantini, M.; Tremolada, Carlo; Tiozzo, M.; Nosadini, A; Zaninotto, Giovanni; Norberto, Lorenzo; Peracchia, A.

doi:10.1007/bf02966125

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“…We used this screening technique in 340 consecutive patients with esophageal diseases at risk for esophageal carcinoma, i.e. peptic esophagitis, benign strictures, achalasia, diverticula, and benign neoplasms: inflammatory alterations were detected in 35.3% of the patients, low-grade dysplasia in 4.8%, and severe dyspla sia-in situ carcinoma in 2.6% [7]. Endoscopy plus vital staining and cytohistologic examination have the greatest diagnostic accuracy in detecting early cancer of the esoph agus [8,9].…”

Section: Discussionmentioning

confidence: 99%

Early Squamous Cell Carcinoma of the Esophagus: Diagnosis and Management

Peracchia¹,

Ruol²,

Bonavina³

et al. 1989

Dig Surg

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Out of 1,338 esophageal carcinomas observed from 1980 to 1987, 171 were clinically staged as early cancers. 150 of 171 patients underwent esophagectomy, and an early cancer was pathologically confirmed in 61. Hospital mortality was 3.3% (2 of 61). The 5-year survival rate of mucosal (n = 10) and submucosal (n = 51) tumors was 100 and 33%, respectively. Neoplastic recurrence was detected in 9 patients, all of whom were operated on for a submucosal tumor. We think that mucosal tumors can be cured with surgical resection, whereas submucosal cancers may need a multimodality treatment. During the last 3 years of the study, 10 patients with a clinical diagnosis of early cancer who were not candidates for surgery underwent endoscopic laser therapy: until now, no patients died with neoplastic recurrence.

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Section: Discussionmentioning

confidence: 99%