La Marche, Commune de Lussac-les-Châteaux (Vienne)

Lwoff, Stéphane

doi:10.3406/bspf.1943.4983

Cited by 4 publications

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“…The first two stages are outside the scope of the present discussion. LWOFF (1943) and KNIGHT (1947-48) have each proposed "loss mutation" to explain development of heterotrophy, symbiosis and parasitism among protozoa and bacteria, based in part upon the demonstration of a number of microbial species which can be arranged in a nutritional series with respect to consecutive genetic defects in a single biosynthetic chain. Knight has proposed that two genetic blocks in one synthetic sequence could explain a permanent nutritional requirement on the basis of improbability of two independent reverse mutations occurring simultaneously in the same cell.…”

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confidence: 99%

Studies of a Purine-Requiring Mutant Strain of Escherichia Coli. Ii. Selection of Revert Strains and Its Evolutionary Significance

Guthrie

1958

Genetics

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N a previous publication (GUTHRIE 1949), certain characteristics of a purine-1 requiring mutant strain of Escherichia coli, 9661-01, were described, including its ability to undergo reversion (change to purine-independence, or P+ ) as shown by optimal growth at suboptimal concentrations of purine. Reversion occurred much more frequently in a complex medium (B) than in a minimal glucose-salts medium (A).This report includes studies of selection between the P (9661-01 parent)

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confidence: 99%