La pyélonéphrite emphysémateuse bilatérale à Candida glabrata : une entité exceptionnelle

Harrabi, Hajer; Marrakchi, Chakib; Daoud, E.; Elleuch, E.; Hammami, B.; Maaloul, I; Lahiani, D.; Mnif, J.; Jemâa, Mounir Ben

doi:10.1016/j.nephro.2010.05.005

Cited by 11 publications

(6 citation statements)

References 8 publications

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“…[1] Predominantly caused by bacterial pathogens, fungal etiology has been implicated in many case reports. [23] EPN is still an uncommon disease with no clear-cut guidelines for diagnosis and management. We therefore, report our experience on the course and outcome of the disease with conservative versus surgical management.…”

Section: Introductionmentioning

confidence: 99%

Emphysematous pyelonephritis: Outcome with conservative management

et al. 2013

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Emphysematous pyelonephritis is a life-threatening condition characterized by necrotising gas forming infection of the renal parenchyma. We describe eight patients seen over a period of 2 years, 62.5% males and 37.5% females with age range between 21 and 65 years. About 75% patients had diabetes mellitus. Six patients were managed conservatively. One patient required nephrectomy with percutaneous drainage and one patient died without surgical intervention.

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Section: Introductionmentioning

confidence: 99%

Emphysematous pyelonephritis: Outcome with conservative management

et al. 2013

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“…[9] There are only few case reports describing fungus as an etiological factor. [34] Our patient is the first reported case of EPN caused by Candida parapsilosis. The patient did not require any form of surgical intervention which is usually required in most of the cases.…”

Section: Discussionmentioning

confidence: 96%

“…Fungal etiology has rarely been reported with Candida albicans, Candida tropicalis, candida glabrata and Cryptococcus usually implicated. [34] We report a case of EPN where candida parapsilosis was grown from urine culture and patient responded to medical management in the form of antifungals. This case is being reported because of two reasons: (1) to our knowledge, this case is the first report of EPN caused by Candida parapsilosis in a diabetic patient.…”

Section: Introductionmentioning

confidence: 99%

Emphysematous Pyelonephritis Caused by Candida Parapsilosis: An Unknown Etiological Agent

et al. 2012

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Emphysematous pyelonephritis (EPN) a rare complication commonly seen in diabetic patients is a necrotising gas producing infection of the renal parenchyma and perinephric tissue predominantly caused by uropathogenic bacteria. Fungi have been rarely reported as the etiological agents, isolated from blood and/ or urine culture. We report a case of EPN caused by a rare etiological agent. A 60 year old diabetic female with no previous history of hospitalization presented to us with a short history of febrile illness associated with abdominal pain. Investigations revealed unilateral EPN “Wan type 1”. Patient was treated with systemic antifungal therapy as per culture sensitivity and it alone proved to be an effective treatment of this clinically difficult condition. Patient was discharged in a satisfactory clinical condition. A rare etiology should always be kept in mind while evaluating a case of EPN.

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“…This is the first report of fungal EPN in a kidney allograft. After an extensive review of the literature, we have not found any cases of EPN of fungal etiology in KT patients, and there were only 15 cases reporting its etiology in native kidneys in nontransplant population; 14 of them (93.3%) had DM, 7 (46.7%) required nephrectomy, and 5 (33.3%) died (Table 1) [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Fulminant Emphysematous Pyelonephritis by <b><i>Candida glabrata</i></b> in a Kidney Allograft

Cases-Corona

Shabaka

Gonzalez-Lopez

et al. 2020

Nephron

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Emphysematous pyelonephritis (EPN) is a rare and serious necrotizing infection that is potentially life-threatening. It has been seldom reported in kidney grafts and is usually caused by Gram-negative bacteria, with some case reports caused by anaerobic bacteria, and has been closely associated with poorly controlled diabetes mellitus (DM) and urinary tract structural abnormalities. There are no reports of EPN of fungal etiology in kidney grafts. We present a case of a 53-year-old kidney transplant recipient with a history of DM, active vesicoureteral reflux, and recurrent urinary tract infections who developed EPN in the kidney allograft caused by Candida glabrata, 3 weeks after starting treatment with empagliflozin, with an aggressive course that required urgent transplant nephrectomy.

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La pyélonéphrite emphysémateuse bilatérale à Candida glabrata : une entité exceptionnelle

Cited by 11 publications

References 8 publications

Emphysematous pyelonephritis: Outcome with conservative management

Emphysematous pyelonephritis: Outcome with conservative management

Emphysematous Pyelonephritis Caused by Candida Parapsilosis: An Unknown Etiological Agent

Fulminant Emphysematous Pyelonephritis by <b><i>Candida glabrata</i></b> in a Kidney Allograft

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